https://www.selleckchem.com/products/gsk046.html We found that topography and morphological features of the substrate are the properties that mainly drives astrocytes adhesion and survival, over the long term, while they do not alter the cell function. Specifically, aligned PCL fibres induced in astrocytes a dramatic actin-cytoskeletal rearrangement as well as focal adhesion point number and distribution. Interestingly, structural changes observed in elongated astrocytes are not correlated with alterations in their electrophysiological properties. Our results indicated that PCL electrospun fibres are a permissive substrate that can be tuned to selectively alters astrocytes structural components while preserving astrocytes function. The results open the view for the use of PCL based electrospun fibres to target astrocytes for the treatment of brain dysfunction such as injuries or chronical disease.Nanotechnology has revolutionized many fields and produced nanostructures are promising materials for different industries. Nanoadsorbents as an emerging class of nanostructures can have potential applications for the separation and removal of both hazardous materials (such as heavy metals from water) and useful ingredients (such as vitamins and natural pigments from food wastes). The present study introduces a novel nanoadsorbent based on the ternary combination of zero valent iron/graphene oxide/active carbon (nZVI/GO-AC) with different formulations and using ultrasonication for improved physical properties. The nanocomposites were prepared by sodium borohydride reduction of graphene oxide, active carbon and ferrous sulfate under a nitrogen atmosphere and ultrasonication. Characterization of the developed nanocomposites was done by instrumental techniques, such as FTIR, VSM, FE-SEM, XRD, EDS, AFM and Raman analysis. The results indicated that the size of particles was 50 nm in the blank sample; however, when GO entered the composition, the particle size switched to less t