https://www.selleckchem.com/ Rechargeable lithium-metal batteries with a cell-level specific energy of >400 Wh kg-1 are highly desired for next-generation storage applications, yet the research has been retarded by poor electrolyte-electrode compatibility and rigorous safety concerns. We demonstrate that by simply formulating the composition of conventional electrolytes, a hybrid electrolyte was constructed to ensure high (electro)chemical and thermal stability with both the Li-metal anode and the nickel-rich layered oxide cathodes. By employing the new electrolyte, Li∥LiNi0.6 Co0.2 Mn0.2 O2 cells show favorable cycling and rate performance, and a 10 Ah Li∥LiNi0.8 Co0.1 Mn0.1 O2 pouch cell demonstrates a practical specific energy of >450 Wh kg-1 . Our findings shed light on reasonable design principles for electrolyte and electrode/electrolyte interfaces toward practical realization of high-energy rechargeable batteries. To develop a simulation model for GammaMed Plus high dose rate Ir brachytherapy source in TOPAS Monte Carlo software and validate it by calculating the TG-43 dosimetry parameters and comparing them with published data. We built a model for GammaMed Plus high dose rate brachytherapy source in TOPAS. The TG-43 dosimetry parameters including air-kerma strength S , dose-rate constant Λ, radial dose function g (r), and 2D anisotropy function F(r,θ) were calculated using Monte Carlo simulation with Geant4 physics models and NNDC Ir spectrum. Calculations using an old Ir spectrum were also carried out to evaluate the impact of incident spectrum and cross sections. The results were compared with published data. For calculations using the NNDC spectrum, the air-kerma strength per unit source activity S /A and Λ were 1.0139×10 U/Bq and 1.1101cGy.h .U , which were 3.56% higher and 0.62% lower than the reference values, respectively. The g (r) agreed with reference values within 1% for radialbe used for future studies. The impact of updated incident spectrum an