However, the causality between road passenger transport and road transport CO2 emissions is bidirectional.  https://www.selleckchem.com/products/disodium-r-2-hydroxyglutarate.html  Finally, comprehensive policy options like subsidizing environmental-friendly technologies, developing green transport infrastructure, and enacting decarbonizing regulations are suggested to address the G20 countries' environmental challenges.Invasive species exert a strong impact on the trophic structure and functioning of the ecosystem they occupy. A modeling software globally used to assess these impacts is Ecopath with Ecosim. This study measures the effects of two invasive species, African catfish Clarias gariepinus, in the food web of the Karapuzha reservoir ecosystem in India. The findings show that the two invasive species directly and indirectly influence several ecosystem elements. The high level of niche overlap (92%) and strong competition for similar resources was exhibited by C. gariepinus. The adverse effects of African catfish on all fish and crustaceans in the reservoir were revealed by mixed trophic impact. Oreochromis mossambicus impacts were both positive and negative. It had a beneficial impact on its predator aquatic birds and was negative towards minnows. This study will help fishery managers to make informed decisions for ecosystem-based fishery management of fish resources.This study was aimed at elucidating the protective effects of 18β-glycyrrhetinic acid (18βGA) against acrylamide (Acr)-induced cellular damage in diabetic rats. Rats were randomly assigned into eight groups (n = 8) following 12 h of fasting control group, a single dose of 50 mg/kg streptozotocin (STZ) intraperitoneally (diabetic group), 50 mg/kg 18βGA orally after 2 weeks from STZ injection (18βGA group), 20 mg/kg Acr after 1month from STZ injection (Acr group), STZ plus Acr (STZ-Acr group), STZ plus 18βGA (STZ-18βGA group), Acr plus 18βGA (Acr-18βGA group), or STZ plus Acr plus 18βGA (STZ-Acr-18βGA group). Administration of 18βGA alone increased GSH, GSH-PX, SOD, and CAT in both liver and kidneys. While STZ injection was associated with diabetic and oxidative stress changes as indicated by the higher serum glucose, cholesterol, creatinine, IL-1β, IL-6, TNF-α, and antioxidant enzyme activities, together with increased lipid peroxides and decreased antioxidant biomarkers in the liver and kidneys. Similarly, the co-administration of STZ and Acr was associated with similar, more augmented effects, compared to STZ alone. The administration of 18βGA normalized STZ and Acr-induced elevations in oxidative defense variables in the liver and kidney tissues and blood biomarkers. Thus, our study demonstrated that the damaging effects of Acr were more exaggerated in diabetic rats. Furthermore, it showed the ability of 18βGA to inhibit reactive oxygen species generation and restore the antioxidant defenses in diabetic rats with Acr-induced liver and kidney cytotoxicity.With the rapid development of logistics park, how to evaluate and optimize the ecological efficiency of logistics park to achieve its sustainable development has become a concern of academia. In order to achieve this goal, this paper puts forward a method based on emergy, which processes the data in a unified dimension. By constructing the ecological efficiency evaluation model of logistics park, it quantitatively evaluates the ecological efficiency of logistics park, and analyzes the correlation between various factors and ecological efficiency. The application results of H logistics park show that fuel oil, information technology, net profit, and waste gas are closely related to the ecological efficiency of logistics park, and the correlation coefficients are 0.8248, -0.6949, 0.8544, and 0.7661, respectively. On this basis, the paper puts forward some suggestions to improve the ecological efficiency of the logistics park. This paper provides theoretical and methodological support for the evaluation and optimization of the ecological efficiency of the logistics park.595-nm pulsed dye laser and fractional CO2 laser have been demonstrated effective to treat hypertrophic scar. The underlying mechanism may involve transforming growth factor-beta1 (TGFβ1) and proliferating cell nuclear antigen (PCNA), but remains to be clarified. Our study was performed to investigate how 595-nm pulsed dye laser combined with fractional CO2 laser treats hypertrophic scars in a rabbit model through regulating the expression of TGFβ1 and PCNA. Twenty-four New Zealand white rabbits were randomly divided into control group, pulsed dye laser group, fractional CO2 laser group, and pulsed dye laser + fractional CO2 laser (combination) group. Surgical wounds were made and allowed to grow into hypertrophic scars at day 28. Next, 595-nm pulsed dye laser (fluence 15 J/cm2; square 7 mm; pulse duration 10 ms) was used in pulsed dye laser and combination group, while fractional CO2 laser (combo mode, deep energy 12.5 mJ; super energy 90 mJ) in fractional CO2 laser and combination groups, once every 4 weeks). The combination of 595-nm pulsed dye laser with fractional CO2 laser can improve the morphology and histology of hypertrophic scars in a rabbit model through inhibiting the expression of TGFβ1 and PCNA protein. Our findings can pave the way for new clinical treatment strategies for hypertrophic scars.To evaluate the local temperature at corneal tissue after applying single laser pulse from six commercial devices; Medilex™, Katana laser-soft, MEL90, Technolas-Teneo317, Alcon EX500, and PulzarTMZ1. The temperature distribution is simulated using finite element solution of the Penne's bio-heat transfer equation on a 3-D model of human cornea using the manufacturer's assigning parameters. The obtained results showed that the heating effect of Katana laser soft is 40% lower than MEL90 and Pulzar™ Z1, while the broad beam Medilex™ showed the minimum temperature rise especially at 248-nm laser radiation. The change in laser parameters selected for ablation has significant effect on the corneal local temperature. The broad beam-based device produces lower local corneal temperature than other flying spot types.