https://www.selleckchem.com/products/acetylcysteine.html evaluation time (p = 0.001), and lower stress values were found after spark erosion regardless of the manufacturing group (p = 0.016). In conclusion, although milled frameworks exhibited the best biomechanical behavior, frameworks manufactured by additive technologies presented acceptable values of screw-loosening torque, strain and stress. Ceramic veneer did not negatively interfere in the biomechanical tests of the study, and clinically acceptable marginal misfit was achieved after spark erosion. Therefore, such 3D printing technologies seem to be feasible for the manufacturing of full-arch implant-supported frameworks.The implant surface and tissue experience strain when micro-motion occurs at the bone-implant interface under physiological loading. Moreover, strain is also introduced on the surface during mechanical processing of biomedical devices. Both these situations can induce phase transformation depending on the degree of stability of the microstructural constituents. In this regard, we elucidate here the interplay between mechanically-induced phase transformation (strain-induced martensite) in austenitic stainless steel on osteoblast functions. Strain-induced martensite significantly impacted cellular functions, notably, cell attachment, cell-surface interactions, proliferation, and synthesis of prominent proteins (fibronectin, actin, and vinculin). Strain-induced martensite favorably modulated cellular activity and contributed to small differences in hydrophilicity in relation to the non-strained austenitic stainless steel surface. The study provides a pathway for tuning biological functionality via microstructural control facilitated by mechanical strain.Tooth enamel has an important mechanical function for human dental health, yet characterizing its mechanical properties is not trivial due to its complex nanoporous structures. We examined the distribution of hardness and modulus across the lingua