The 'intermediate' population was intermediate between the 'front' and the 'core' populations regarding reproductive traits, but showed the highest growth rates. The life-history traits that varied most among populations were gonad weight, fecundity, gonado-somatic index, condition and growth in the first years of life. Inter-individual variability of life-history traits was lower in the front of the invasive range than in the core and intermediate area. The observed plasticity in life-history appears to favour production of large numbers of offspring in newly-colonised areas in the initial stages of invasion and at the edge of the expanding range. In longer-established populations, at the core of invasive range, a strategy for greater competitiveness under intra-specific competition appears to be favoured.Anthropogenic activities are seriously endangering the conservation of biodiversity worldwide, calling for urgent actions to mitigate their impact on ecosystems. We applied machine learning techniques to predict the response of freshwater ecosystems to multiple anthropogenic pressures, with the goal of informing the definition of water policy targets and management measures to recover and protect aquatic biodiversity. Random Forest and Gradient Boosted Regression Trees algorithms were used for the modelling of the biological indices of macroinvertebrates and diatoms in the Tagus river basin (Spain). Among the anthropogenic stressors considered as explanatory variables, the categories of land cover in the upstream catchment area and the nutrient concentrations showed the highest impact on biological communities. The model was then used to predict the biological response to different nutrient concentrations in river water, with the goal of exploring the effect of different regulatory thresholds on the ecosystem status. Specifically, we considered the maximum nutrient concentrations set by the Spanish legislation, as well as by the legislation of other European Union Member States. According to our model, the current nutrient thresholds in Spain ensure values of biological indices consistent with the good ecological status in only about 60% of the total number of water bodies. By applying more restrictive nutrient concentrations, the number of water bodies with biological indices in good status could increase by almost 40%. Moreover, coupling more restrictive nutrient thresholds with measures that improve the riparian habitat yields up to 85% of water bodies with biological indices in good status, thus proving to be a key approach to restore the status of the ecosystem.To evaluate the transboundary pollution of organic aerosols from Northeast Asia, a highly time-resolved measurement of organic compounds was performed in March 2019 at Oki Island located in Japan, which is a remote site and less affected by local anthropogenic sources. PM2.5, water-soluble organic carbon (WSOC) concentrations, and WSOC fraction in PM2.5 showed high values on March 22-23 (high-WSOC period (HWSOC)) when the air mass passed through the area where many fire spots were detected in Northeast China. Biomass burning tracers showed higher concentration, especially levoglucosan exceeded 1 μg/m3 during the HWSOC than the low-WSOC period (LWSOC). Notably, high time-resolved measurements of biomass burning tracers and back trajectory analysis during HWSOC revealed a difference in the variation of lignin pyrolyzed compounds and anhydrous sugars on 22 and 23 March. The air mass passed to different areas in Northeast China in which fire spots were detected, such as the eastern area on the 22nd and the westerpositions and the characterization of organic aerosols in downwind regions of Northeast China.Ultraviolet (UV) filters are compounds utilized in many manufacturing processes and personal care products such as sunscreen to protect against UV-radiation. These highly lipophilic compounds are emerging contaminants of concern in aquatic environments due to their previously observed potential to bioaccumulate and exert toxic effects in marine ecosystems. Currently, research into the toxic effects of UV filter contamination of freshwater ecosystems is lacking, thus the present study sought to model the effects of acute and chronic developmental exposures to UV filters avobenzone, oxybenzone and octocrylene as well as a mixture of these substances in the freshwater invertebrate, Daphnia magna, at environmentally realistic concentrations. Median 48-hour effect and lethal concentrations were determined to be in the low mg/L range, with the exception of octocrylene causing 50% immobilization near environmental concentrations.  https://www.selleckchem.com/products/Mycophenolic-acid(Mycophenolate).html  48-hour acute developmental exposures proved to behaviourally impair daphnid phototactic response; however, recovery was observed following a 19-day post-exposure period. Although no physiological disruptions were detected in acutely exposed daphnids, delayed mortality was observed up to seven days post-exposure at 200 μg/L of avobenzone and octocrylene. 21-day chronic exposure to 7.5 μg/L octocrylene yielded complete mortality within 7 days, while sublethal chronic exposure to avobenzone increased Daphnia reproductive output and decreased metabolic rate. 2 μg/L oxybenzone induced a 25% increase in metabolic rate of adult daphnids, and otherwise caused no toxic effects at this dose. These data indicate that UV filters can exert toxic effects in freshwater invertebrates, therefore further study is required. It is clear that the most well-studied UV filter, oxybenzone, may not be the most toxic to Daphnia, as both avobenzone and octocrylene induced behavioural and physiological disruption at environmentally realistic concentrations.Exposure levels of neonicotinoids (NEO) in young children remain unknown, despite their widespread use and the plausible vulnerability of toddlers to environmental toxicants. Herein we aimed to clarify the exposure levels and sources of NEOs in young Japanese children. Disposable diapers were collected from 1036 children (16-23 months old) participating in an adjunct study of the Japan Environment and Children's Study between 2015 and 2016. Six NEOs and one metabolite in urine extracted from a diaper from each child were analyzed using high-performance liquid chromatography-tandem mass spectrometry. A relative potency factor approach was used to assess the cumulative exposure to NEOs equivalent to dinotefuran levels (DINRPF). The 95th percentile urinary concentration of DINRPF was 157 μg/L and 380 μg/g creatinine (Cr). Receiver operating characteristic curve analyses for the propensity scores of the possible exposure-related factors revealed that the discriminatory powers determining whether Cr-adjusted and Cr-unadjusted DINRPF concentrations exceeding the 95th percentile values were higher for the amount of each foodstuff ingested on the survey day (areas under the curve were 0.