009). Among the 42 symptomatic, the mean age of males was significantly higher than that of females (66 vs 57 years, P = 0.04), while the opposite was observed in the 58 asymptomatic patients (60 vs 73 years, P = 0.0018). Conclusions Recovery from OD or GD was rapid, occurring within 4 weeks in most patients. Chemosensory dysfunctions in women was less frequent, but longer lasting. The value of our study is its focus on a population of hospitalized patients significantly older than those previously described, and the additional data on gender differences.Objectives Several studies have reported that younger children suffer from increased incidence and more severe episodes of acute mastoiditis (AM) than older children, whereas other researchers have found the opposite. The aim of our study was to describe the occurrence, clinical, and microbiological aspects of AM in children 6 months or younger, and compare them with the results in an older reference age band. Methods The medical files of children hospitalized with a diagnosis of AM during 2001-2016 were retrospectively reviewed. Diagnosis of AM was based on the presence of clinical signs of acute otitis media (AOM) accompanied by two or more of the following auricle protrusion, retro-auricular erythema, swelling, and local tenderness. Children were divided into two age bands, 6 months or younger, and older than 6 months. Results Fifty patients in the young age band and 335 in the older reference age band were included. Bilateral AOM was identified in 14 (28%) children under 6 months, and 50 (14.9%) in the rehildren. We suggest that the treatment approach should be the same for both groups.Purpose Recently, it has been reported that patients with acute vestibular syndrome (AVS) could present a marked enhancement of the semi-circular canals, involving mostly the superior semi-circular canals on delayed inner ear MRI. Methods We reported one patient having AVS and another one having superior semi-circular canal dehiscence syndrome (SCDS) who underwent delayed inner ear MRI performed 4 h after contrast media administration. Results On delayed inner ear MRI, a marked enhancement of the superior semi-circular canal was observed in both patients. Although the clinical presentation is clearly not the same, the co-existence between these two disorders is possible. For this reason, in patients with AVS, the presence of a marked enhancement of the superior semi-circular canal should rule out the presence of a co-existing SCDS on temporal bone CT, particularly if the patient reported cochlear symptoms such as pulsatile tinnitus and/or autophony. Conclusion To our knowledge, this is the first report showing this finding on delayed inner ear MRI in a patient with SCDS. In AVS patients, this radiological anomaly could be particularly disturbing and should rule out the presence of a co-existing SCDS.In this letter, we describe an attachment on conventional headbands recommended for the postoperative period in prominent ear patients to confidently wear surgical masks without disturbing the posterior auricular incision. LEVEL OF EVIDENCE V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.Background Double incision mastectomy with free nipple grafts (DIFNG) offers more flexible nipple-areola complex (NAC) resizing and repositioning in transmale and gender non-conforming individuals. The cis-male NAC has a smaller diameter, oval shape and lateral position. If nipple grafts are performed without having these considerations, aesthetics can be dissatisfying. We aim to describe the nipple split sharing technique during chest wall masculinization surgery comparing surgical, patient-reported outcomes (PRO) and aesthetic results with the conventional technique. Methods This was a retrospective review of transmale patients who underwent DIFNG from January 2017 to January 2019. The cohort was divided into two groups conventional and the splitting technique. Demographics, intraoperative and postoperative outcomes were recorded. In addition, PRO using Body-Q scale and aesthetic results using a Likert-based scale were analyzed. Results Thirty-four patients (68 breasts) underwent DIFNG. A total of 32 breastne ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266. Breast Surgery.Objective To evaluate the effect of Chinese medicine (CM) treatment on survival time and quality of life (QOL) in patients with small cell lung cancer (SCLC). Methods This was an exploratory and prospective clinical observation. Patients diagnosed with SCLC receiving CM treatment were included and followed up every 3 months. The primary outcome was overall survival (OS), and the secondary outcomes were progression-free survival (PFS) and QOL. Results A total of 136 patients including 65 limited-stage SCLC (LS-SCLC) patients and 71 extensive-stage SCLC (ES-SCLC) patients were analyzed. The median OS of ES-SCLC patients was 17.27 months, and the median OS of LS-SCLC was 40.07 months. The survival time was 16.27 months for SCLC patients with brain metastasis, 9.83 months for liver metastasis, 13.43 months for bone metastasis, and 18.13 months for lung metastasis. Advanced age, pleural fluid, liver and brain metastasis were risk factors, while longer CM treatment duration was a protective factor. QOL assessment indicated that after 6 months of CM treatment, scores increased in function domains and decreased in symptom domains. Conclusion CM treatment might help prolong OS of SCLC patients. Moreover, CM treatment brought the trend of symptom amelioration and QOL improvement.  https://www.selleckchem.com/products/VX-770.html  These results provide preliminary evidence for applying CM in SCLC multi-disciplinary treatment.In this paper, differences in the pollen levels detected in two parts of Salamanca (a city in central-western Spain) have been revealed using two volumetric samplers. One sampler was located in the city centre and the other in a semi-natural zone. The two sampling devices were separated by a distance of 1.4 km. During the two-year study period, the most abundant allergenic pollen type was Poaceae, with peak values being detected in May. Maximum values were registered between April and June. The values obtained in both zones with regard to pollen seasonality were similar during the peak day, but the abundance of pollen grains detected in the semi-urban was higher, except for Olea pollen type. The atmospheric pollen season was similar in duration, except for some types belonging to the genera Plantago and Urticaceae, which showed divergent values most probably due to the influence of climatic conditions. The meteorological parameter most significantly correlated to pollen concentration was temperature, being negative for winter species and positive for plants preferring warmer climates.