https://www.selleckchem.com/products/sch58261.html formulations, and pain management across Europe. The quality of end-of-life care services directly affects the end-of-life quality of life of patients and their families. At present, there are no standard tools in China for assessing the quality of dying and death (QODD) of critical intensive care unit (ICU) patients. This study aimed to introduce the Chinese version of the QODD questionnaire for family members of ICU patients, after transcultural adaptation and validation, to provide an effective instrument for assessing the quality of end-of-life care of ICU patients in China, fill the gap in the evaluation of the quality of end-of-life care of critical ICU patients in China, and offer a theoretical basis and practical guidance during purposeful intervention. This study involved the main adult caregivers or principal family members of 149 dying critically ill patients. The original QODD scale was translated using the double forward and backward method. Nine cultural adaptation experts adapted the Chinese version of the QODD scale for completion by ffor evaluating the quality of death among patients who die in the ICU and can be applied to clinical practice and research. The Chinese version of the QODD questionnaire for family members of ICU patients is a reliable and effective instrument for evaluating the quality of death among patients who die in the ICU and can be applied to clinical practice and research. No clinical trials have examined the effect of netupitant/palonosetron (NEPA) on chronic nausea in patients with cancer. In this pilot randomized trial, we assessed the efficacy of NEPA and placebo on chronic nausea. This double-blind, parallel, randomized trial enrolled patients with cancer and chronic nausea for at least 1month, intensity ≥4/10 and not on moderately or highly emetogenic systemic therapies. Patients started with a placebo run-in period from days 1 to 5; those without a placebo response proce