Cell-to-Cell Heterogeneity within Trypanosomes.
 nd cognitive functions, and AF, HbA1c, and hs-CRP were independent factors correlated with increased FIM-Cognitive score.PURPOSE Fractures of the clavicle, which has an important location and function in the upper extremity and shoulder joint, compose 10% of all fracture cases. During the osteosynthesis of clavicle fractures and in the post-operative period of patients, considering the detailed morphometric and topographic properties of the nutrient foramen of clavicle is important to avoid the disruption of arterial nutrition of the clavicle and prevent unexpected injuries. The aim of this study was to investigate the morphometric properties of the nutrient foramen of clavicle in more detail using computedtomography images. METHODS Computed tomography images of 116 healthy individuals (56 women/60 men) who had no pathology history were included in the presented study. Computed tomography images were reconstructed three-dimensionally using free-licensed Horos v3.3.3 software. Then, distances from clavicle's nutrient foramen to sternal end, anterior and posterior edges of the clavicle were measured. Statistical analyses were completed using SPSS v21 software. RESULTS Our results demonstrated that the nutrient foramen of clavicle was located closer to the sternal end of the clavicle. The shortest distance to the sternal edge of clavicle was measured as 3.3 cm. Analyses of gender differences indicated that statistically significant differences were in favor of men. However, topographic properties of the clavicle's nutrient foramen were not affected by age. CONCLUSION Nutrient foramen is mostly located closer to the sternal end of clavicle. Especially during osteosynthesis of clavicle fractures at the sternal end, maintaining the arterial supply of clavicle is of great importance for increasing the post-operative life quality of patients.PURPOSE To analyze the morphologic features of accessory anterolateral talar facet (AALTF) on MRI that can assist in detecting this entity, identify any associated structural changes and also define its MRI prevalence. METHODS Two radiologists retrospectively evaluated 140 ankle MRI scans for the presence of AALTF, complimentary anterior calcaneal extension facet and angle of Gissane measurement. One observer evaluated the scans for other structural details including AALTF length, cartilage thickness, bone marrow edema, hind foot coalition and talar beaking. RESULTS There was a good inter-observer agreement for the detection of AALTF on MRI (Kappa = 0.64).  https://www.selleckchem.com/products/LBH-589.html  AALTF was present in 33 out of 140 (23.6%) scans. There was no significant difference in the prevalence of AALTF between male and female subjects (P = 0.71). No significant difference in age between those with and those without AALTF (P = 0.96). Angle of Gissane was significantly smaller in ankles with AALTF (P = 0.0367, observer 1 and 0.0003, observer 2). AALTF had a mean length of 7 mm and was covered with cartilage in 25/33 (75.8%) with mean cartilage thickness of 1.4 mm. Complimentary cartilage covered anterior calcaneal facet was demonstrated in 10/33 (30.3%) and had a mean cartilage thickness of 2.5 mm. Talar beaking was more prevalent in ankles with AALTF showing an anterior calcaneal extension facet than those without the latter feature (P = 0.02). CONCLUSION AALTF is a frequently observed feature on ankle MRI, with good inter-observer reliability for its detection. When present, it is often opposed by a cartilage covered anterior calcaneal extension facet, which can be associated with talar beaking.PURPOSE Posterior tibial inclination of the knee joint should be considered during anterior cruciate ligament reconstruction and total knee replacement surgery. This inclination is called the posterior tibial slope (PTS) angle. The PTS differs among populations and the aim of this study was to determine the mean PTS in a Turkish population. METHODS PTS was measured retrospectively on lateral knee X-rays (n = 1024). The angle between the line connecting the anterior and posterior points of the lateral tibial plateau and the tibial longitudinal axis was taken as the PTS angle. Intra- and inter-observer agreement regarding the measurements on 20 X-rays were checked.  https://www.selleckchem.com/products/LBH-589.html  RESULTS The mean PTS angle for the entire cohort was 8.36 ± 3.3° (range 2.1-18.7°); it was 8.57 ± 3.4° (range 2.3-17.4°) in men and 8.16 ± 3.2° (range 2.1-18.7°) in women. Although no significant correlation was detected between PTS and age, PTS was higher in men than in women. CONCLUSION The increasing number of total knee replacement surgeries has increased the need for studies on implant mismatch. In this study, reference PTS values were determined for a Turkish population. It may be beneficial to use patient-specific implants in some cases.PURPOSE Spinal angiolipomas are benign spinal epidural tumors consisting of mature fat cells with angiomatous components. These tumors are rare in children and there are no definite management guidelines. METHOD To the best of our knowledge, only five cases of spinal angiolipomas have been reported in children below 12 years. This article discusses the presentation, diagnostics, and surgical tips for the management of a case of spinal angiolipoma. RESULT In this paper, we present a one and half-year-old child presenting with a spontaneous spinal epidural hematoma from a spinal angiolipoma and underscore the importance of early surgery in a benign disease for a good outcome. CONCLUSION Overall neurological recovery and prognosis following timely intervention for spinal angiolipomas are good.PURPOSE Pure arterial malformations of the brain are rare vascular lesions. METHODS We present a 10-year-old healthy boy who presented with an incidental finding of pure arterial malformation. RESULTS Our case seems to represent the second description of pure arterial malformation discovered incidentally in a child. CONCLUSION We review the clinical presentation, angiographic findings, and management of our case in the context of other reported pediatric cases.Degenerative cysts associated with an unstable os odontoideum in pediatric patients are uncommon lesions. Reported treatments of such lesions have varied and yielded mixed results with the optimal surgical strategy remaining unclear. The authors report the clinical and surgical outcome of a 13-year-old patient presenting with degenerative cyst adjacent to an abnormal os odontoideum motion segment. The patient was asymptomatic from this lesion which was an incidental finding while undergoing workup for atypical headaches. Clinical and radiologic findings, operative details, and postoperative outcome are described. The patient was successfully treated with posterior cervical fusion without direct cyst decompression. Complete resolution of the cyst was demonstrated on magnetic resonance imaging at 6 months. Computed tomography 8 months postoperatively showed solid bony fusion and normal alignment. Regarding treatment goals in pediatric patients with os odontoideum degenerative cysts, the current case and literature review supports posterior instrumented fusion without direct surgical cyst resection.