https://www.selleckchem.com/products/epz015666.html ObjectiveEffects of drugs or immunotherapy on the quality of life of adult patients with allergic rhinitis（AR） were assessed using the rhinoconjunctivitis quality of life questionnaire（RQLQ）. MethodA total of 142 patients were included, including 37 patients receiving specific immunotherapy（SIT）（SIT group）. The remaining 105 patients received standardized drug treatment, and were divided into 87 cases in the receiving drug application instruction group（A1 group） and 18 cases in the non-receiving drug application instruction group（A2 group） according to whether or not receiving the drug application guidance group. According to whether or not receiving supervision of drug applications, they were divided into 33 cases of receiving drug application supervision group（B1 group） and 72 cases of non-receiving drug application supervision group（B2 group）. Using telephone follow-up, RQLQ was used to evaluate the patients 'daily activities, sleep, non-nasal-eye symptoms, nasal symptoms, eye symptoms, practical problems,mproved by improving medication guidance and publicity.ObjectiveTo investigate the effects of life events and emotional stress on short-term curative efficacy in adolescents with low-tone sudden deafness （LTSD）. MethodVarious psychological stress measures were conducted on adolescent patients with recently diagnosed LTSD before initiating treatment, and the follow-up hearing condition were also obtained after 3 months of treatment. Using logistic regression analysis, we identified the predictors of life stress and emotion symptoms of treatment response in these adolescent patients. ResultTreatment were effective in 103 cases and ineffective in 41 cases. The stress, depression and anxiety symptoms of the high-life events in the ineffective group were significantly higher than those in the effective group. The logistics regression analysis showed that life stress [OR（95%CI）=1.16（1.07-2.42） ] and depressive sympto