A biomass-derived sponge-like carbonaceous aerogel was prepared through a two-step procedure, including hydrothermal carbonization and freeze-drying process. The aerogel was employed as the solvent holder for liquid-phase microextraction of organophosphorus pesticides, ethion, and chlorpyrifos (as the model compounds), prior to determination by secondary electrospray ionization-ion mobility spectrometry. The carbonaceous aerogel is an appropriate candidate to be used as the solvent holder due to some properties such as three-dimensional structure, porous nature, and very low density. So, the aerogel, including extraction solvent, can tumble on the top of the sample solution, without loss of solvent during its agitation. A comparison of the extraction efficiency was performed at similar conditions between the proposed method and single-drop microextraction, as well as hollow-fiber solvent bar microextraction. Different parameters affecting the extraction efficiency, such as stirring rate, salt concentration, temperature, and extraction time were investigated by using the response surface methodology. The linear dynamic range was in the ranges 1-30 and 1-70 μg L-1 with regression coefficients of 0.9973 and 0.9956 for ethion and chlorpyrifos, respectively. The limit of detection was 0.09 and 0.21 μg L-1 for ethion and chlorpyrifos, respectively. The method was used for extracting analytes from environmental water and vegetable samples, with the spiking recoveries in the range 80-121%. Graphical abstract Schematic representation of three-dimensional biomass-derived carbonaceous aerogel as the solvent holder in solvent bar microextraction (as a mode of the liquid-phase microextraction method). It was used for the extraction of two kinds of organophosphorus pesticides prior to the determination by ion mobility spectrometry.BACKGROUND Synchronous double cancer of the colon and stomach accompanied by liver metastasis is rare. It is often difficult to determine an appropriate treatment strategy for multiple liver metastases of synchronous gastric cancer and colorectal cancer. Multidisciplinary treatment is required based on the progression and location of each tumor and chemotherapy for complete resection. CASE PRESENTATION A 57-year-old male who complained of acute abdominal pain and fever visited his local hospital. He underwent emergent surgery for peritonitis caused by a gastric perforation. The cytodiagnosis of ascites did not show any tumor cells. There was a liver metastasis in the lateral segment of the liver. We performed a primary closure of the defect and then applied an omentum flap. After surgery, the patient was diagnosed as having synchronous cStage IV transverse colon cancer with multiple liver metastases and cStage IIB gastric cancer. The [18F]-fluorodeoxyglucose (FDG) positron emission tomography/computed tomogratransverse colon was ypT2 (MP) with grade 2 therapeutic effects and that there were no atypical cells in the gastric tumor and multiple liver nodules (pathological complete response). CONCLUSION The SOX plus bevacizumab regimen could be an option for controlling tumor progression in synchronous double cancer of the colon and stomach with liver metastasis and led to the complete resection of such tumors.PURPOSE Currently, no consistent guidelines for CT scans used within PET/CT examinations are available. This systematic review provides an up-to-date overview of studies to answer the following questions What are the specific CT protocols used in PET/CT? What are the possible purposes of requiring a CT study within a PET/CT scan? Is the CT protocol obtained from a dosimetric optimisation study? MATERIALS AND METHOD PubMed/MEDLINE, Cochrane Library, Embase and Scopus were systematically searched for relevant studies in accordance with the PRISMA statement. The literature search was conducted from January 2007 until June 2019. Data derived from studies were standardized in order to reduce possible biases, and they were divided into clinically homogeneous subgroups (adult, child or phantom). Subsequently, we divided the CT protocol intents into 3 types (anatomic localization only, attenuation correction only and diagnostic purpose). A narrative approach was used to summarise datasets and to investigate their hetopment of new technologies.BACKGROUND Cancer is a risk factor for perioperative deep venous thrombosis and pulmonary embolism (DVT/PE). However, there is a paucity of data on non-malignant digestive diseases. In this study, we aimed to investigate the incidence of DVT/PE among patients, following surgery for acute appendicitis and other digestive diseases. METHODS We retrospectively reviewed the records of patients who underwent surgical procedures involving the digestive system between April 2018 and March 2019 attended by anesthesiologists (n = 536). RESULTS DVT/PE developed in seven patients (7/77, 9.1%, 95% confidence interval [CI] 3.7-17.8%) after surgery for acute appendicitis, and in six patients (6/83, 7.2%, 95%CI 2.7-15.1%) after elective surgery for colorectal cancer. Among the acute appendicitis group, six patients (6/30 20.0%) with complicated appendicitis (gangrenous or perforated appendicitis), and one patient (1/47 2.1%) with simple appendicitis showed postoperative DVT/PE. Patients with complicated appendicitis had a higher risk of DVT/PE than those with simple appendicitis with an odds ratio of 11.5 (95%CI 1.3-101.1). CONCLUSIONS Although patients with acute appendicitis lack three of the risk factors for DVT/PE (cancer, long operative time, and older age), their 95% CI for the incidence of DVT/PE was comparable to that of patients undergoing elective surgery for colorectal cancer. Therefore, caution must be exercised during the perioperative period for preventing DVT/PE.OBJECTIVES This study aimed to investigate the relationship between aging and tooth loss on masseter muscle quantity and quality. MATERIALS AND METHODS This cross-sectional study was conducted among 112 participants (in their 20s to 90s) who were independent in activities of daily living and were able to follow verbal commands.  https://www.selleckchem.com/products/p22077.html  Exclusion criteria comprised participants with a lack of molar occlusal support, diseases that could affect muscle function, or temporomandibular disorder. Age, tooth loss, and weight were documented, and masseter muscle thickness (MMT) and masseter muscle echo intensity (MMEI) were measured using an ultrasonic diagnostic apparatus. A multiple regression analysis was used to determine the relationship between MMT, MMEI, aging, and tooth loss, among each sex. The significance level in the statistical analysis was p  less then  0.05. RESULTS In males, aging was a significant explanatory variable for MMT (adjusted R2 = 0.27), while both aging and weight were significantly associated with MMEI (adjusted R2 = 0.