In this modern era, environmental pollution is the biggest problem attached to industrialization. This study tries to ensure the relationship between industrialization and CO2 emissions in Pakistan for the time period 1980-2018 by using nonlinear ARDL model while controlling for urbanization, GDP, and human capital variables as a likely factor of CO2 emissions. Our foremost study objective is to examine whether or not the outcome of industrialization on CO2 emissions is symmetric or asymmetric for Pakistan that is one of the core suppliers to CO2 in South Asia, as the emissions were 0.82 million tons in 2018. Our result approves the presence of an asymmetric effect of industrialization shocks on CO2 emissions both in the short run and long run. The results reveal that industrialization increases emissions and deindustrialization decrease emissions, in short as well as long run, in Pakistan. Moreover, our finding also advises that urbanization and GDP variables have exerted a positive impact on CO2 emissions. Based on the findings, some policy suggestions are proposed for Pakistan.The carbamazepine (CBZ) abatement is herein evaluated using catalytic ozonation at different NiO concentrations as catalyst 100, 300, and 500 mg L-1, revealing its total destruction after 5 min of reaction either by conventional or catalytic ozonation.  https://www.selleckchem.com/products/mps1-in-6-compound-9-.html  The NiO incorporation in the reactor does not increase the destruction rate, but the catalyst presence enhances the partial mineralization of the contaminant by conversion into oxalic and formic acids and the removal of total organic carbon (TOC) associated with the formation of oxidant species such as hydroxyl radical. Evidence for this behavior is the accumulation rate of the above acids which rise proportionally to the NiO concentration. The highest NiO concentration (500 mg L-1) reached a maximum TOC removal of 79.2%, which exceeds by 50% the outcome of the conventional treatment. The accumulation-decomposition profiles of oxalic and formic acids suggest the occurrence of simultaneous reaction mechanisms (hydroxyl radicals and complex formations) on the catalyst during CBZ ozonation. According to XPS analysis, the presence of nitrogen species in the NiO-ozonated was attributable to byproducts of CBZ decomposition. The toxicity bioassay based on Lactuca sativa seeds demonstrate that ozonated samples attained similar plant germination than the reference substance (water) after 120 min of treatment. This result is comparable with or without the catalyst presence, indicating the formation of non-toxic accumulated byproducts at the end of the ozonation reaction.In this study, perceived moral obligations were included in the protection motivation theory (PMT) model to explain people's intentions to participate in climate change mitigation behaviors. Empirical data and structural equation modeling results of a nationwide cross-sectional survey in Taiwan confirmed the higher explanatory power of the moral extension PMT model than that of the original PMT model. As expected, threat and coping appraisal of climate change affect protection motivation. In addition, perceived moral obligation affects protection motivation. This protection motivation enhances the intention to participate in climate change mitigation behaviors. The mediation effect of protection motivation was also verified in the moral extension PMT model. Practical implications and suggestions are proposed for the government and related authorities as well as environmental groups to encourage people to participate in climate change mitigation behaviors.Abamectin has been widely used in agriculture and animal husbandry. It has been shown that abamectin exposure could induce multiple toxic effects on non-target organisms, but the underlying mechanism is still largely unknown. In the current study, the mechanism of abamectin-induced cytotoxicity was investigated in mouse embryonic fibroblast cells. Abamectin treatment could cause oxidative stress in cells (beginning at 0.4 μg/ml, 0.5 μM) and the ROS overproduction was mainly induced by the impacts of abamectin on the activities of CAT (beginning at 4.4 μg/mL, 5 μM), SOD (beginning at 8.7 μg/mL, 10 μM), GPx (beginning at 4.4 μg/mL, 5 μM), and contents of GSH (beginning at 4.4 μg/mL, 5 μM), which are important components of the ROS elimination pathway in mammal cells. Abamectin could impair DNA integrity (as demonstrated by increased 8-OHdG/dG ratio) in cells, even at environmental level (0.4 μg/mL, NOAEL), and abamectin-induced oxidative stress was one of the main reasons for the DNA damage that occurred in cells. Moreover, pretreatment with the inhibitor of JNK and ATM/ATR signaling pathway could partially rescue the decreased cell viability, indicating that oxidative stress and DNA damage might be involved in abamectin-induced cytotoxicity. These findings could provide new insights into the mechanism of abamectin-induced cytotoxicity and should be useful for a more comprehensive assessment of the adverse effects of abamectin.BACKGROUND Across the globe, diseases secondary to environmental exposures have been described, and it was also found that existing diseases have been modified by exposure to environmental chemicals or an environmental factor that has been found in their pathogenesis. The Institute of Medicine has shared a permanent concern related to the nations environmental health capacity since 1988. MAIN BODY Contemporary imaging methods in the last 15 years started reporting alterations in different human systems such as the central nervous system, cardiovascular system and pulmonary system among others; evidence suggests the existence of a human environmental disease network. The primary anatomic regions, affected by environmental diseases, recently assessed with imaging methods include Brain (lead exposure, cerebral stroke, pesticide neurotoxicity), uses MRI, DTI, carotid ultrasonography and MRS; Lungs (smoke inhalation, organophosphates poisoning) are mainly assessed with radiography; Gastrointestinal system (chronic inflammatory bowel disease), recent studies have reported the use of aortic ultrasound; Heart (myocardial infarction), its link to environmental diseased has been proved with carotid ultrasound; and Arteries (artery hypertension), the impairment of aortic mechanical properties has been revealed with the use of aortic and brachial ultrasound. CONCLUSIONS Environmental epidemiology has revealed that several organs and systems in the human body are targets of air pollutants. Current imaging methods that can assess the deleterious effects of pollutants includes a whole spectrum radiography, US, CT and MRI. Future studies will help to reveal additional links among environmental disease networks.