33, 95% CI [0.80, 2.24]). Offspring gender discrimination was associated with offspring heavy drug use (RRR = 2.09, 95% CI [1.07, 4.06]) and not associated with moderate/light use (RRR = 1.44, 95% CI [0.86, 2.42]), but post hoc tests revealed no significant group differences. Conclusions Findings suggest that perceived offspring gender discrimination is associated with early drug use initiation. Gender discrimination, particularly at an early age, has a potential to cause harm, including drug use. Implementation of policies that foster environments that eliminate gender bias and discrimination at an early age should be prioritized. Gender-responsive treatment merits consideration by substance use treatment providers. (PsycInfo Database Record (c) 2020 APA, all rights reserved).In this Letter, a rational and stepwise method for the solution-phase synthesis of asymmetric Au split nanorings by adopting Au nanoprisms as a template has been demonstrated. The selective chemical etching of Au nanoprism tips activated the surface reactivity of edges and led to the selective deposition of Pt at the periphery of Au nanoplates. By controlling the total amount of Pt on the edges, different degrees of split Au@Pt nanorings were obtained; the subsequent Au coating around the Au@Pt scaffold eventually resulted in asymmetric Au hexagonal split nanorings. Their surface plasmonic features as a function of split degrees were investigated, including straight nanorods, bent nanorods, split nanorings, and full nanorings. The electrical field focusing using single-particle surface-enhanced Raman spectroscopy was evaluated under different polarization angles of the incident light for two different structures with the point gap and line gap between two arms.Surface-enhanced Raman spectroscopy (SERS) is a promising cellular identification and drug susceptibility testing platform, provided it can be performed in a controlled liquid environment that maintains cell viability. We investigate bacterial liquid-SERS, studying plasmonic and electrostatic interactions between gold nanorods and bacteria that enable uniformly enhanced SERS. We synthesize five nanorod sizes with longitudinal plasmon resonances ranging from 670 to 860 nm and characterize SERS signatures of Gram-negative Escherichia coli and Serratia marcescens and Gram-positive Staphylococcus aureus and Staphylococcus epidermidis bacteria in water. Varying the concentration of bacteria and nanorods, we achieve large-area SERS enhancement that is independent of nanorod resonance and bacteria type; however, bacteria with higher surface charge density exhibit significantly higher SERS signal. Using cryo-electron microscopy and zeta potential measurements, we show that the higher signal results from attraction between positively charged nanorods and negatively charged bacteria. Our robust liquid-SERS measurements provide a foundation for bacterial identification and drug testing in biological fluids.Li metal batteries (LMBs) are crucial for electrifying transportation and aviation. Engineering electrolytes to form desired solid-electrolyte interphase (SEI) is one of the most promising approaches to enable stable long-lasting LMBs. Among the liquid electrolytes explored, fluoroethylene carbonate (FEC) has seen great success in leading to desirable SEI properties for enabling stable cycling of LMBs. Given the many facets to desirable SEI properties, numerous descriptors and mechanisms have been proposed. To build a detailed mechanistic understanding, we analyze varying degrees of fluorination of the same prototype molecule, chosen to be ethylene carbonate (EC) to tease out the interfacial reactivity at the Li metal/electrolyte. Using density functional theory (DFT) calculations, we study the effect of mono-, di-, tri-, and tetra-fluorine substitutions of EC on its reactivity with Li surface facets in the presence and absence of Li salt. We find that the formation of LiF at the early stage of SEI formation, posited as a desirable SEI component, depends on the F-abstraction mechanism rather than the number of fluorine substitution. The best illustrations of this are cis- and trans-difluoro ECs, where F-abstraction is spontaneous with the trans case, while the cis case needs to overcome a nonzero energy barrier. Using a Pearson correlation map, we find that the extent of initial chemical decomposition quantified by the associated reaction free energy is linearly correlated with the charge transferred from the Li surface and the number of covalent-like bonds formed at the surface.  https://www.selleckchem.com/products/Nolvadex.html  The effect of salt and the surface facet have a much weaker role in determining the decompositions at the immediate electrolyte/electrode interfaces. Putting all of this together, we find that tetra-FEC could act as a high-performing SEI modifier as it leads to a more homogeneous, denser LiF-containing SEI. Using this methodology, future investigations will explore -CF3 functionalization and other backbone molecules (linear carbonates).With the coming of the big data age, the resistive switching memory (RSM) of three-dimensional (3D) high density shows a significant application in information storage and processing due to its simple structure and size-scalable characteristic. However, an electrical initialization process makes the peripheral circuits of 3D integration too complicated to be realized. Here a new forming-free SiC x H-based device can be obtained by tuning the Si dangling bond conductive channel. It is discovered that the forming-free behavior can be ascribed to the Si dangling bonds in the as-deposited SiC x H films. By tuning the number of Si dangling bonds, the forming-free SiC x H RSM exhibits a tunable memory window. The fracture and connection of the Si dangling bond conduction pathway induces the switching from the high-resistance state (HRS) to the low-resistance state (LRS). Our discovery of forming-free SiC x H resistive switching memory with tunable pathway opens a way to the realization of 3D high-density memory.We analyze how the photorelaxation dynamics of a molecule can be controlled by modifying its electromagnetic environment using a nanocavity mode. In particular, we consider the photorelaxation of the RNA nucleobase uracil, which is the natural mechanism to prevent photodamage. In our theoretical work, we identify the operative conditions in which strong coupling with the cavity mode can open an efficient photoprotective channel, resulting in a relaxation dynamics twice as fast as the natural one. We rely on a state-of-the-art chemically detailed molecular model and a non-Hermitian Hamiltonian propagation approach to perform full-quantum simulations of the system dissipative dynamics. By focusing on the photon decay, our analysis unveils the active role played by cavity-induced dissipative processes in modifying chemical reaction rates, in the context of molecular polaritonics. Remarkably, we find that the photorelaxation efficiency is maximized when an optimal trade-off between light-matter coupling strength and photon decay rate is satisfied.