6% of males, 34.2% of females and 43.9% of total cancer survivors would have been eligible for statin therapy under the 2018 American College of Cardiology/American Heart Association guidelines and Korean Coronary Heart Disease Risk Score guidelines. The rate of undertreatment of dyslipidemia increased with age and length of time since cancer diagnosis.
 
  Nearly 50% of cancer survivors remain untreated although they are eligible for statin therapy. This emphasizes the need for more attention to prevent atherosclerotic cardiovascular disease among cancer survivors.
 Nearly 50% of cancer survivors remain untreated although they are eligible for statin therapy. This emphasizes the need for more attention to prevent atherosclerotic cardiovascular disease among cancer survivors.
  Hemodynamic monitoring and cardiac output (CO) assessment in the ICU have been trending toward less invasive methods. Carotid blood flow (CBF) was suggested as a candidate for CO assessment. The present study aimed to test the value of carotid artery ultrasound analysis in prediction of mortality in pediatric patients with septic shock.
 
  Forty children with septic shock were included in the study. Upon admission, patients were subjected to careful history taking and thorough clinical examination.  https://www.selleckchem.com/products/3-deazaneplanocin-a-dznep.html  The consciousness level was assessed by the Glasgow Coma Scale (GCS). Laboratory assessment included complete blood count, C-reactive protein, arterial blood gases, serum electrolytes, and liver and kidney function tests. Electrical cardiometry was used to evaluate hemodynamic parameters. Patients were also subjected to transthoracic 2-D echocardiography. CBF was evaluated using GE Vivid S5 ultrasound device through dedicated software. At the end of study, 14 patients (35.0%) died. It was found that survivors had significantly higher CBF when compared non-survivors [median (IQR) 166.0 (150.0-187.3) versus 141.0 (112.8-174.3), p = 0.033]. In addition, it was noted that survivors had longer ICU stay when compared with non-survivors [16.5 (9.8-31.5) versus 6.5 (3.0-19.5) days, p = 0.005]. ROC curve analysis showed that CBF could significantly distinguish survivors from non-survivors [AUC (95% CI) 0.3 (0.11-0.48), p = 0.035] (Fig 2). Univariate logistic regression analysis identified type of shock [OR (95% CI) 28.1 (4.9-162.4), p<0.001], CI [OR (95% CI) 0.6 (0.43-0.84), p = 0.003] and CBF [OR (95% CI) 0.98 (0.96-0.99), p = 0.031]. However, in multivariate analysis, only type of shock significantly predicted mortality.
 
  CBF assessment may be a useful prognostic marker in children with septic shock.
 CBF assessment may be a useful prognostic marker in children with septic shock.Air quality in China has gradually been improving in recent years; however, the Beijing-Tianjin-Hebei (BTH) region continues to be the most polluted area in China, with the worst air quality index. BTH and its surrounding areas experience high agglomeration of heavy-polluting manufacturers that generate electric power, process petroleum and coal, and carry out smelting and pressing of ferrous metals, raw chemical materials, chemical products, and non-metallic mineral products. This study presents evidence of the air pollution impacts of industrial agglomeration using the Ellison-Glaeser index, Herfindahl-Hirschman index, and spatial autocorrelation analysis. This was based on data from 73,353 enterprises in "2+26" atmospheric pollution transmission channel cities in BTH and its surrounding areas (herein referred to as BTH "2+26" cities). The results showed that Beijing, Yangquan, Puyang, Kaifeng, Taiyuan, and Jinan had the highest Ellison-Glaeser index among the BTH "2+26" cities; this represents the highest enterprise agglomeration. Beijing, Langfang, Tianjin, Baoding, and Tangshan also showed a low Herfindahl-Hirschman index of pollutant emissions, which have a relatively high degree of industrial agglomeration in BTH "2+26" cities. There was an inverted U-shaped relationship between enterprise agglomeration and air quality in the BTH "2+26" cities. This means that air quality improved with increased industrial agglomeration up to a certain level; beyond this point, the air quality begins to deteriorate with a decrease in industrial agglomeration.Ecological compensation is an important means of basin pollution control, the existing researches mainly focus on the government level ignoring the important role of enterprises. Therefore, this paper introduces enterprises into the process of ecological compensation. Firstly, suppose the ecological compensation system composed of government and enterprises, the government is in the dominant position. The ecological compensation input of the government and enterprise will produce social reputation, and the ecological compensation of enterprise will also produce advertising effect. Consumer demand will be affected by social reputation and advertising effect. Then, the compensation strategies of the government and enterprise are analyzed by constructing the differential game model. The research shows that under certain conditions, the cost-sharing mechanism can realize the Pareto improvement of the benefits of government, enterprise and the whole system. Under the cooperative mechanism, the benefit of the government, enterprise and the whole system is optimal. Finally, the validity of the conclusion is verified by case analysis, and the sensitivity analysis of the relevant parameters is carried out. The conclusion can provide reference for government to establish sustainable watershed ecological compensation mechanism.The need for excess weight gain prevention in disadvantaged young children is widely recognised. Early Childhood Education and Care teachers are potential key actors in early interventions to prevent overweight and obesity. This study examines the effects of a preschool-based intervention for teachers in promoting healthy eating and physical activity in young children. A cluster randomised controlled trial was conducted at 41 preschools in a deprived area of Amsterdam, The Netherlands. The intervention consisted of 2 programmes that were applied in succession A Healthy Start and PLAYgrounds for TODdlers. The study period was 9 months. Primary outcomes were assessed via questionnaires and included teachers' knowledge, attitude, food/activity-related practices, and level of confidence in promoting healthy behaviours. Secondary outcomes in this study were teachers' and children's BMI (z-score), body composition, dietary intake and physical activity level. Intention-to-treat analyses were performed using linear mixed models.