https://www.selleckchem.com/products/polyethylenimine.html Physical inactivity is considered a problem with great impact on morbidity and mortality. There is a necessity to combat this behavior through an assessment of barriers and benefits perceived by subjects. The current study aimed to measure exercise intention, in addition to identifying physical exercise predictors, including perceived barriers and benefits among healthcare providers (HCPs) in Ain Shams University Hospitals. A cross-sectional study was performed on a sample(n = 327) of healthcare providers (physicians and nurses) in Ain Shams University Hospitals in Cairo, Egypt, using anonymous self-administrated questionnairesand relevant scales. Out of 327 healthcare providers approached, 52.6% of them were males and the mean age of participants was (29.34 ± 7.84 years). Physical exercise was reported by 44.6% of participants. The most significant factors associated with physical exercise engagement were male gender, participants with lower body mass index (BMI), and those with higher perceived "lifiers of exercise is recommended to encourage healthcare personnel to follow a healthy lifestyle as a role model to their patients and to act as health promoters to them. Glioblastoma (GBM) has a survival rate of around 2 years with aggressive current standard of care. While other tumors have responded favorably to trials combining immunotherapy and chemotherapy, GBM remains uniformly deadly with minimal increases in overall survival. GBM differ from others due to being isolated behind the blood brain barrier, increased heterogeneity and mutational burden, and immunosuppression from the brain environment and tumor itself. We have reviewed clinical and preclinical studies investigating how different doses (dose intense (DI) and metronomic) and timing of immunotherapy following TMZ treatment can eradicate tumor cells, alter tumor mutational burden, and change immune cells. Recent clinical trials with standard of ca