https://www.selleckchem.com/products/nazartinib-egf816-nvs-816.html 3, which was a statistically significant ( < 0.001). By the ROC curve, the cutoff value of PNI was 32.3 and area under the curve was 0.888. The sensitivity, specificity, positive predictive value, and negative predictive value were 91.28% (95% confidence interval [CI] 88.2-93.8), 71.09% (95% CI 66.5-75.4), 76.5% (95% CI 73.7-79.2), and 88.8% (95% CI 85.3-91.5), respectively. The PNI is an easy and an applicable biomarker to estimate life expectancy in TCPs. The PNI is an easy and an applicable biomarker to estimate life expectancy in TCPs. Patients with cancer receiving radiotherapy experiences fatigue and psychological distress. Now a days there has been growing interest towards managing these symptoms with non-pharmacological treatments, But researches related to effect of progressive muscle relaxation therapy on fatigue and psychological distresses related to admitted patients are limited hence the aim of the study to evaluate the effect of progressive muscle relaxation therapy on fatigue and psychological distress in Cancer patients during Radiotherapy. Aim of the study to evaluate the effect of progressive muscle relaxation therapy on fatigue and psychological distress in Cancer patients during Radiotherapy. The study design was single blinded randomized control trial. Total of 50 patients, for both intervention and control group 25 patients were included. The intervention group patients received P.M.R. therapy of 20 min. given for 3 times/week of total period of 3 weeks, whereas the control group received conventional treatment with no added intervention. Fatigue symptom inventory and hospital anxiety and depression scale used as an outcome measures. Paired -test used for FSI to compare among intervention and control group and results were showing statistical significant difference ( < 0.05), similarly pre and post improvement was observed in both the groups for HADS. Between group comparison