https://www.selleckchem.com/products/mf-438.html 05) villus height to crypt depth ratio than the other groups; Furthermore, the higher (p<0.05) threshold cycle values of lactic acid bacteria and lower (p<0.05) threshold cycle values of Clostridium, Enterobacter and Escherichia coli were also observed in the SPCF group, and the sucrase and maltase activity was higher (p<0.05) in the SPCF group than the other groups in duodenum and ileum. Soft pellet creep feed improved pre-weaning feed intake and decreased the negative effects of weaning stress in the intestine in piglets. Soft pellet creep feed improved pre-weaning feed intake and decreased the negative effects of weaning stress in the intestine in piglets. Omasum is an important site an important site for the absorption of short chain fatty acids. The major route for the transport of acetate is via sodium hydrogen exchanger (NHE). However, a discrepancy in the symmetry of sodium and acetate transport has been previously reported, the mechanism of which is unclear. In this study, we investigated the possible role of carbonic anhydrase (CA) for this asymmetry. Omasal tissues were isolated from healthy sheep (N=3) and divided into four groups; pH 7.4 and 6.4 alone and in combination with Ethoxzolamide. Electrophysiological measurements were made using Ussing chamber and the electrical measurements were made using computer controlled voltage clamp apparatus. Effect(s) of CA inhibitor on acetate and sodium transport flux rate of Na22 and 14C-acetate was measured in three different flux time periods. Data were presented as mean ± standard deviation and level of significance was ascertained at p ≤ 0.05. Mucosal to serosal flux of Na (JmsNa) was greater than mucosal to serosal flux of acetate (JmsAc) when the pH was decreased from 7.4 to 6.4. However, the addition of carbonic anhydrase inhibitor almost completely abolished this discrepancy (JmsNa ≈ JmsAc). The results of the present study suggest that the additional proton