https://www.selleckchem.com/products/ti17.html ositions.Increase of medical knowledge, technical innovation together with a demographic change, and increase of stone incidence in daily practice challenges guideline preparation and clinical studies. Increasing interdisciplinary collaboration in stone treatment can also be demonstrated in the number of affiliated professional and working groups in the current guideline update. The following case illustrates treatment options in a symptomatic patient harbouring bilateral stones and metabolic risk factors. Decision guidance for treatment and recurrence prevention measures are presented on the basis of expert opinion and available published evidence. Robotic surgery was introduced into general surgery more than 20years ago. Shortly afterwards, Horgan performed the first robotic-assisted esophagectomy in 2003 in Chicago. The aim of this manuscript is to elucidate new developments and training methods in robotic surgery with acost-benefit analysis for robotic-assisted Ivor Lewis esophagectomy. Systematic literature search regarding new technology and training methods for robotic surgery and cost analysis of intraoperative materials for hybrid and robotic-assisted Ivor Lewis esophagectomy. Robotic-assisted esophageal surgery is complex and involves an extensive learning curve, which can be shortened with modern teaching methods. New robotic systems aim at the use of image-guided surgery and artificial intelligence. Robotic-assisted surgery of esophageal cancer is significantly more expensive that surgery without this technology. Oncological short-term and long-term benefits need to be further evaluated to support the higher cost of robotic esophageal cancer surgery. Oncological short-term and long-term benefits need to be further evaluated to support the higher cost of robotic esophageal cancer surgery.Diabetic foot syndrome (DFS) is the most frequent reason for major amputations in Germany. The majority of foot lesions are