https://www.selleckchem.com/products/4-aminobutyric-acid.html The paper investigates what type of motivation can be given for adopting a knowledge-based decision theory (hereafter, KBDT). KBDT seems to have several advantages over competing theories of rationality. It is commonly argued that this theory would naturally fit with the intuitive idea that being rational is doing what we take to be best given what we know, an idea often supported by appeal to ordinary folk appraisals. Moreover, KBDT seems to strike a perfect balance between the problematic extremes of subjectivist and objectivist decision theory. We argue that these alleged advantages do not stand up to a closer scrutiny KBDT inherits the same kinds of problems as alternative decision theoretic frameworks but doesn't retain any of the respective advantages. Moreover, differently from other knowledge-action principles advanced in the literature, KBDT cannot fully explain the intuitive connections between knowledge and rational action. We conclude that the most serious challenge for knowledge-based decision theorists is to provide a substantive rationale for the adoption of such a view.Processes of cold-air pool (CAP) erosion in an Alpine valley during south foehn are investigated based on a real-case large-eddy simulation (LES). The event occurred during the second Intensive Observation Period (IOP 2) of the PIANO field experiment in the Inn Valley, Austria, near the city of Innsbruck. The goal is to clarify the role of advective versus turbulent heating, the latter often being misrepresented in mesoscale models. It was found that the LES of the first day of IOP 2 outperforms a mesoscale simulation, is not yet perfect, but is able to reproduce the CAP evolution and structure observed on the second day of IOP 2. The CAP exhibits strong heterogeneity in the along-valley direction. It is weaker in the east than in the west of the city with a local depression above the city. This heterogeneity results from di