https://www.selleckchem.com/products/AZD1480.html The Internet of Things (IoT)-based target tracking system is required for applications such as smart farm, smart factory, and smart city where many sensor devices are jointly connected to collect the moving target positions. Each sensor device continuously runs on battery-operated power, consuming energy while perceiving target information in a particular environment. To reduce sensor device energy consumption in real-time IoT tracking applications, many traditional methods such as clustering, information-driven, and other approaches have previously been utilized to select the best sensor. However, applying machine learning methods, particularly deep reinforcement learning (Deep RL), to address the problem of sensor selection in tracking applications is quite demanding because of the limited sensor node battery lifetime. In this study, we proposed a long short-term memory deep Q-network (DQN)-based Deep RL target tracking model to overcome the problem of energy consumption in IoT target applications. The proposed method is utilized to select the energy-efficient best sensor while tracking the target. The best sensor is defined by the minimum distance function (i.e., derived as the state), which leads to lower energy consumption. The simulation results show favorable features in terms of the best sensor selection and energy consumption.There were an estimated 10 million new cases of tuberculosis (TB) disease in 2019. While over 90% of individuals successfully control Mycobacterium tuberculosis (Mtb) infection, which causes TB disease, HIV co-infection often leads to active TB disease. Despite the co-endemic nature of HIV and TB, knowledge of the immune mechanisms contributing to the loss of control of Mtb replication during HIV infection is lacking. Mucosal-associated invariant T (MAIT) cells are innate-like T cells that target and destroy bacterially-infected cells and may contribute to the control of Mtb infection.