https://www.selleckchem.com/products/ITF2357(Givinostat).html Chemotherapy treatment often causes side-effects like fatigue in cancer patients. The treatment and diagnosis of cancer can cause depression, which could lead to inflammatory changes in the body, and it is involved in fatigue pathophysiology. This study aims to determine the relationship between depression and fatigue. A cross-sectional design was used, and a consecutive sampling method with a sample of 30 children with cancer aged 8-12 years. This study used two instruments, which are the Fatigue Onkologi Anak-Allen (FOA-A) questionnaire and Centre for Epidemiological Studies Depression Scale for Children (CES-DC). The results showed a significant relationship between depression and fatigue (p=0.003) and between types of cancer and fatigue (p=0.018). These results indicated that children with cancer and depressive symptoms felt higher fatigue. Nurses need to assess the fatigue and depression felt by children so they can perform appropriate nursing interventions to reduce their fatigue.Patient safety is an important for health care services in the hospital setting. The most difficult obstacle in ensuring patient safety is creating a safety. The objective of this study was to determine the correlation between the hospital work environment, nurses' characteristics, and patient safety. The method was a descriptive correlative study with a cross-sectional approach. The data were obtained from 123 ward nurses through using valid and reliable questionnaires. The results showed a significant relationship between hospital work environment and nurses' characteristics (education level, length of service, and training concerning patient safety) (p.05). Findings indicate that the hospital work environment and nurses' characteristics are related to patient safety. The study recommended to build a model of patient's safety culture that includes all aspects that influence patients' safety culture.This research was condu