https://www.selleckchem.com/products/bix-01294.html The ASGE's GIE Editorial Board reviewed original endoscopy-related articles published during 2019 in GIE and 10 other leading medical and gastroenterology journals. Votes from each individual member were tallied to identify a consensus list of 10 topic areas of major advances in GI endoscopy. Individual board members summarized important findings published in these 10 areas of disinfection, artificial intelligence, bariatric endoscopy, adenoma detection, polypectomy, novel imaging, Barrett's esophagus, third space endoscopy, interventional EUS, and training. This document summarizes these "Top 10" endoscopic advances of 2019.Diclofenac is an FDA approved drug used in the treatment and management of acute and chronic pain associated with inflammatory conditions, especially those involving the musculoskeletal system. These include osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Topically, it can treat actinic keratosis. Diclofenac is also FDA approved for ophthalmic administration for the extraction of cataracts, pain in the eye, and photophobia. It is a non-steroidal anti-inflammatory drug (NSAID) and, although it can help to manage the symptoms of pain during inflammatory processes, it cannot reverse or prevent chronic joint damage seen with osteoarthritis and rheumatoid arthritis. Diclofenac was synthesized in 1973 and is the most widely prescribed NSAID worldwide.Deferoxamine (DFO) is FDA approved to treat iron overload, either acute or chronic. The definition of iron overload is serial ferritin levels above 800 to 3000 ng/mL . The FDA has not approved DFO as first-line therapy for hereditary hemochromatosis unless there is a contraindication to phlebotomy. Clinicians can also use DFO is also used as an off-label treatment for aluminum toxicity in chronic kidney disease (CKD) patients.An aneurysm is an abnormal dilatation or bulging in a blood vessel due to the intrinsic weakness of the vessel w