https://www.selleckchem.com/products/i-brd9-gsk602.html Exercise induced bronchoconstriction (EIB) is common and underdiagnosed phenomenon of yet largely unknown etiology. This study aimed to estimate prevalence of EIB in response to highly demanding skyscraper race and to test its association with race performance and hypothetical predisposing factors. Healthy participants (26 males, 8 females; 31.5 +/- 6.3 years) from mostly running-based amateur sports were measured for forced expiratory volume in first 1 s (FEV1) before and then repeatedly within 10 min after the completion of the 114 m skyscraper upstairs race. Allergy questionnaire (AQUA) data were collected and post-exercise blood lactate was measured. Over 40% of the participants developed >10% decrement in FEV1 shortly after all-out exercise. While EIB response was not associated with questionnaire-based atopic status, training background, gender, age, anthropometrics, pacing and exertion (estimated from the accumulated blood lactate values), participants exhibiting 10%) were slower indicative of poorer fitness due to EIB developing during the exercise already.Excess body fatness is a consequence of a chronic energy surplus (energy intake is greater than energy expenditure). Given the serious health consequences of excess body fatness, factors that influence energy balance and body composition are increasingly important to understand. Methods - A total of 34 adults between the ages of 19-40 years made a laboratory visit in which height, weight, body composition, and cardiometabolic risk factors were quantified. Participants wore accelerometers for 21-28 days, then returned to the laboratory for a second body composition assessment. Changes in weight and body composition were used to quantify energy balance, and data derived from accelerometers provided markers of physical activity and sedentariness. Results - Of the markers of physical activity that we measured, daily step counts expressed relative to fat m