https://www.selleckchem.com/products/cx-4945-silmitasertib.html The pursuit of hedonia and eudaimonia are two ways to fulfill the goal of a "good life". While some studies report that both hedonic and eudaimonic motives improve well-being, others suggest that hedonic motives are counterproductive, raising the question of whether and why eudaimonic motives are more positively associated with well-being. We aimed to identify the distinct associations of hedonic and eudaimonic motives with well-being and investigate whether they are partly mediated by self-control. A total of 2882 college freshmen (1835 females, 1047 males, mean age 18.16 years) completed measures assessing hedonic and eudaimonic motives, self-control, life satisfaction, positive and negative affect, and eudaimonic well-being. Eudaimonic motives were associated with higher life satisfaction, more positive affect, less negative affect, and better eudaimonic well-being. In contrast, hedonic motives were positively associated with life satisfaction, while also being correlated with a greater degree of negative affect and impaired eudaimonic well-being. Self-control mediated the relationships between hedonic and eudaimonic motives and well-being. Eudaimonic and hedonic motives were positively and negatively related to self-control, respectively. Further, high self-control was associated with greater life satisfaction, positive affect, and eudaimonic well-being and lower negative affect. Thus, eudaimonic motives can lead to a better life than hedonic motives because the former enhance self-control, while the latter lower it.Liver fat accumulation is an important pathophysiological feature of non-alcoholic fatty liver disease that may be modulated by dietary supplements (DS). A systematic search of the literature was conducted for randomized controlled trials (RCTs) pertaining to the effect of a DS on liver fat as assessed using quantitative tomographic imaging in human adults. Where feasible, data were pool