https://www.selleckchem.com/products/cpypp.html 4). The obstetric comorbidity index that is most often used may be undervaluing the degree of association with SMM. Hospital discharge diagnosis files and birth certificate records can have misclassifications and may not include all relevant clinical data or social determinants. The period for analysis ended in 2014 to avoid the transition to the International Classification of Diseases, 10th Revision, Clinical Modification, and therefore missed more recent years. Obstetric and, particularly, medical comorbid conditions are increasing among women who develop SMM. The maternal comorbidity index is a promising tool for patient risk assessment and case-mix adjustment, but refinement of factor weights may be indicated. National Institutes of Health. National Institutes of Health. Skilled, high-quality health providers and birth attendants are important for reducing maternal mortality. To assess whether U.S. regional variations in maternal mortality rates relate to health workforce availability. Comparison of regional variations in maternal mortality rates and women's health provider rates per population and identification of a relationship between these measures. U.S. health system. Women of child-bearing age and women's health providers, as captured in federal data sources from the Centers for Disease Control and Prevention, Census Bureau, and Health Resources and Services Administration. Regional-to-national rate ratios for maternal mortality and women's health provider availability, calculated per population for women of reproductive age. Provider availability was examined across occupations (obstetrician-gynecologists, internal medicine physicians, family medicine physicians, certified nurse-midwives), in service-based categories (birth-attending and primary care proviers. None. None.Maternal mortality and severe maternal morbidity are critical health issues in the United States, with unacceptably high rates and racial