https://www.selleckchem.com/products/marimastat.html Patients will be included for 6 months with 3 follow-up times (0, 3, and 6 months) by a sport physician. The primary outcome is the evolution of quality of life score. Secondary outcomes are disability score, fatigue, anxiety-depression, cost-effectiveness and process evaluation. The study protocol has been approved by a French ethics committee (CPP Sud Méditerranée IV, N°ID-RCB 2020-A01916-33). Results will be submitted for publication, at scientific conferences and through press releases. NCT04627714. NCT04627714.A growing body of research has demonstrated that providing learners with self-control over aspects of the learning environment facilitates the learning of a motor skill. In applied group settings, however, the provision of feedback is at times constrained by factors such as instructor availability. The purpose of the present study, therefore, was to examine how learners ostensibly provided self-control over feedback responded when the actual availability of feedback was constrained by a predetermined schedule of a virtual coach's availability to provide feedback. Participants were divided into four feedback groups and completed 72 practice trials of a sequential key-pressing task, with three different goal movement times (900, 1,200, 1,500 ms). The KR100 group received knowledge of results (KR) after every practice trial. The KR50 group received KR on an evenly distributed quasi-randomly determined schedule after 50% of the trials. The SC group had the opportunity to request KR after every trial, but KR was o a role in elevating the number of feedback requests in response to the reduced autonomy environment. The present study aimed to determine the association of skiing speed (SS), range time (RT), and the number of missed targets (MT) with rank in sprint and individual biathlon competitions. Data were collected from the International Biathlon Union's database for 17 seasons (2002/2003-2018/2019). Furth