https://www.selleckchem.com/products/Rapamycin.html ansport. Tight junctions between endothelial cells typically regulate paracellular transportation. Transcellular transport occurs through passive and active mechanisms. Passive transport affected by physicochemical properties such as molecular weight, electrical charge, and lipophilicity and is typically limited to small, lipophilic molecules that are less than 500 Daltons in size. Nutrients and proteins which are larger and less lipophilic transported by active transport mechanisms. Glucose is transported by carrier-mediated transport (CMT) via the GLUT-1 protein, insulin, which undergoes receptor-mediated transcytosis (RMT), and albumin follows adsorptive-mediated transcytosis (AMT).The lymphatic system is a system that drains the leaked tissue fluid back into the circulation. Its components are lymphatic vessels, lymphatic organs, lymph nodes, and widely scattered lymphoid tissue within the connective tissue. Lymph is the tissue fluid flowing through these lymphatic channels. Lymphatic vessels contain valves that prevent the backflow of transported lymph. The lymphatic vessels are so thin that the mere presence of valves gives the lymphatic channels the beaded appearance. Lymph flow from the peritoneum navigates through the thoracic duct to the intrathoracic lymph nodes. This extracellular fluid then returns to the bloodstream. Lymph is usually colorless, but that flowing from the intestinal organs is whitish (milky) due to the massive deposition of fat droplets within it and referred to as chyle. The lymphatic system in the gastrointestinal (GI) tract helps regulate the transport of chyle and balance interstitial fluid. A stimulant, such as feeding, activates lymph flow in the GI tractnd inferior mesenteric. These nodes drain lymph from the GI tract, spleen, gallbladder, pancreas, and liver. The para-aortic nodes, also known as the lumbar aortic nodes, drain lymph from the kidneys, suprarenal glands, testes, ov