https://www.selleckchem.com/pharmacological_epigenetics.html 1) with lower contents in house 1. Regarding the manure under the slatted floor, a tendency for a difference between house 1 and house 2 was found for the content of E. coli (F = 5.55, p less then 0.1) with higher contents in house 1. The floor did not show any significant effect on the physical parameters of litter and manure. The results of this experimental study showed no positive effects on the selected litter parameters, but further studies, especially on-farm experiments are necessary to confirm these results.Hereditary nephropathy is a primary progressive glomerular disease in dogs associated with the c.115A>T mutation in the COL4A4 gene in English cocker spaniel (ECS) dogs. The disease is inherited in an autosomal recessive manner. Hereditary nephropathy has been described in this breed since the late 1940s. To date, there are no data on the prevalence of this disease in Brazil, so the aim of this study was to evaluate the allelic frequency of this mutation in ECS dogs in this country. The DNA samples were purified from blood samples or buccal swabs from 221 ECS dogs. Fragments of the DNA containing the mutation were amplified by PCR and submitted to direct gene sequencing. The allele frequency of the mutation was 0.9%. The presence of the mutation in the ECS dog population in Brazil reveals the importance of performing the genotyping tests in these dogs as a method of diagnosing the disease and identifying heterozygous animals, aiming to reduce clinical cases of disease through mating.The agricultural product market is changing from a producer-orientated to a more consumer-orientated market. Consumer rely on the classification system within the red meat types. Different red meat types and carcass classifications influence the prices of red meat. This study was conducted to determine the price dynamics of different red meat carcasses and carcass classes. It was theorised that the different red mea