https://www.selleckchem.com/products/tas-102.html 001) increased compared to baseline. Patients without POR showed a decrease of Streptococcaceae (FDR=0.003) and Actinomycineae (FDR=0.06). The mucosa-associated microbiota profile had good discriminative power to predict POR, and was superior to clinical risk factors. At month 6, patients experiencing POR had a higher abundance of taxa belonging to Negativicutes (FDR=0.04) and Fusobacteria (FDR=0.04) compared to patients without POR. CONCLUSIONS Microbiota recolonization after ileocecal resection is different between recurrence and non-recurrence patients, with Fusobacteria as the most prominent player driving early POR. These bacteria involved in the early recolonization and POR represent a promising therapeutic strategy in the prevention of disease recurrence. © The Author(s) 2020. Published by Oxford University Press on behalf of European Crohn’s and Colitis Organisation.BACKGROUND AND AIMS Angiosperms vary remarkably in traits such as colour, size and shape of flowers, yet such variation generally tends to be low within species. In deceptive orchids, however, large variation in floral traits has been described, not only between, but also within populations. Nonetheless, the factors driving variation in floral traits in deceptive orchids remain largely unclear. METHODS To identify determinants of variation in floral traits, we investigated patterns of fruit set and selection gradients in the food-deceptive orchid Orchis purpurea, which typically presents large within-population variation in the colour and size of the flowers. Using long-term data, fruit set was quantified in two populations during sixteen consecutive years (2004-2019). Artificial hand pollination was performed to test the hypothesis that fruit set was pollinator limited and that selfing led to decreased seed set and viability. Annual variation (2016-2019) in selection gradients was calculated for three colour traits (brightness, contrast and the n