https://www.selleckchem.com/products/amlexanox.html 87. Spearman's rho was 0.68 for concurrent validity (correlation between total MADRS-S-score and K-SADS MDD severity score). In receiver-operating characteristic analysis, the area under the curve was 0.86 (95% confidence interval 0.78-0.93, p  less then  .001). For all the participants, the highest combined sensitivity and specificity were reached using cut-offs of 15 and 16 (sensitivity 0.82, specificity 0.86). Optimizing sensitivity for MDD, with specificity still ≥0.5, cut off for all was 9, for boys 7 and for girls 10.Conclusion Psychometric properties of MADRS-S showed good reliability and validity as well as satisfying diagnostic accuracy, indicating good to excellent properties for MDD screening of adolescent psychiatric patients.Background The ABILOCO-Kids is a parent-reported outcome measure that quantifies locomotion ability and has been reported to have satisfactory measurement properties. An Arabic version of the scale is needed for Arabic-speaking population.Objective To cross-culturally adapt the ABILOCO-Kids into Arabic and to examine its measurement properties in children with cerebral palsy.Methods Forward and backward translations, then expert committee followed by preliminary testing were conducted to produce the Arabic ABILOCO-Kids. Structural validity of the scale as a unidimensional measure was examined using Rasch analysis. Internal consistency, test-retest reliability, and construct validity of the adapted scale were examined in children with cerebral palsy (N = 154).Results Rasch analysis supported the structural validity of the Arabic ABILOCO-Kids after combining two items (χ2 = 18.17, p = .44). The scale had excellent internal consistency (person separation index = 0.88), excellent test-retest reliability (intraclass correlation coefficient = 0.98) but had a floor effect (24% reaching the minimum score). Eighty percent of the predefined hypotheses regarding the correlation between the Ar