https://www.selleckchem.com/products/ebselen.html Global positioning systems (GPS) imbedded with accelerometer systems (AS) are used in rugby union (RU) to collect information on absolute and relative distances, distances in different speed zones, high-speed running (HSR) distances, repeated high-intensity efforts (RHIE) and collisions and impacts. This information can be used to monitor match play which can then be used to plan training sessions. The objective of this review was to conduct a systematic review of studies which have reported the use of GPS and AS. A systematic review of the use of GPS and AS in both age-grade and senior rugby was conducted. The authors systematically searched electronic databases from January 2010 until March 2020. Keywords included rugby union, GPS, global position* and microtechnology. A total of 51 studies met the eligibility criteria and were included in this review. There was a total of 34 studies utilising GPS and AS in senior RU players (mean ± SD; age 26.2 ± 1.9 years; height 185.7 ± 2.6 cm; mass 101.3 ± 4.2 kg)eview can be used to help coaches assess performances in match play, allow them to plan appropriate training sessions and monitor training load.Three-dimensional transthoracic echocardiography (3D-TTE) provides a semi-automated proximal isovelocity surface area method (3D-PISA) to obtain quantitative parameters. Data assessing regurgitation severity in mitral valve prolapse (MVP) are scarce, so we assessed the 3D-PISA method compared with 2D-PISA and cardiovascular magnetic resonance (CMR) and the role of an eccentricity index. We evaluated the 3D-PISA method for assessing MR in 54 patients with MVP (57 ± 14 years; 42 men; 12 mild/mild-moderate; 12 moderate-severe; and 30 severe MR). Role of an asymmetric (i.e. eccentricity index ≥ 1.25) flow convergence region (FCR) and inter-modality consistency were then assessed. 3D-PISA derived regurgitant volume (RVol) showed a good correlation with 2D-PISA and CMR derived parame