https://www.selleckchem.com/products/ml-7.html In turn, this interaction affects other variables such as the duration of the breeding season and life-history traits. Taken together, our results challenge long-standing hypotheses about the association between sex determination and climate variability. We also show that ambient temperature is important during breeding seasons and it helps explain the effects of sex determination systems on the geographic distribution of extant reptile species. Taken together, our results challenge long-standing hypotheses about the association between sex determination and climate variability. We also show that ambient temperature is important during breeding seasons and it helps explain the effects of sex determination systems on the geographic distribution of extant reptile species. Cinnamomum cassia (C. cassia) is an evergreen tree in China and southern and eastern Asia. In traditional medicine, cinnamon is widely used due to its many bioactivity effects. The aim of the present novel study is to evaluate and make comparison of antioxidant and antiproliferative activities of different extractions of C. cassia bark using seven solvents having different polarities. Solvents polarity gradients start with the solvent of lower polarity, n-hexane and end with water as the highest polar solvent. Among the extracts, acetone extract contains the highest phenolic and flavonoid contents; therefore it is assessed for the ability to protect DNA from damage. The extracts are evaluated for total phenolic, flavonoid contents and antioxidant activities, using FRAP, DPPH, superoxide, and hydroxyl and nitric oxide radicals scavenging assays. DNA damage protecting activity of the acetone extract is studied with comet assay. Each of the extracts is studied for its antiproliferative effect against, MCF-7, MDAMB- 231(breast cancer) and HT29 (colon cancer), using MTT assay. The acetone extract exhibited the highest FRAP value, phenolic and flavonoids conte