The elemental analysis of complex matrices such as superphosphate-fertilizers and agricultural inputs by means of microwave-induced plasma optical emission has been evaluated in the present study. A commercial single superphosphate-fertilizer and three certified reference materials - CRMs (multi-nutrient, phosphate rock and dolomitic limestone) were analysed. Samples were submitted for three different analyte extraction or decomposition procedures; microwave assisted digestion (MAD), extraction by heating on a metallic plate and ultrasound assisted extraction (US). Analyte recovery tests were carried out to evaluate dilutions of the obtained sample solutions to reduce or avoid matrix effects. Better results were obtained for samples submitted for MAD and the concentration values found agreed with those certified or known for the CRMs. Inductively coupled plasma optical emission spectrometry (ICP OES) was employed as an independent technique for analyte determination in the superphosphate-fertilizer submitted for MAD. The concentrations found by both techniques were in agreement with each other for most of the investigated elements. As such, MIP OES has demonstrated good performance for the determination of 19 elements.A mixture of rhodium(iii) hydroxocomplexes formed during the polycondensation process in alkaline media has been fully characterized by the hyphenated high performance liquid chromatography with electrospray ionization mass spectrometry (HPLC-ESI-MS). The baseline separation was achieved using reverse phase ion-pair chromatography (RP-IP-HPLC) in gradient elution mode. When using SDS as the ion pair, the formation of all types of its associates with the molecules of acetonitrile, as well as oligomers of rhodium aquahydroxocomplexes, etc. was taken into consideration. As a result, it was shown that the test mixture is presented by [Rh(H2O)6]3+, [Rh2(μ-OH)2(H2O)8]4+, [Rh3(μ-OH)4(H2O)10]5+, [Rh4(μ-OH)6(H2O)12]6+.In this study, the use of hydride generation atomic fluorescence spectrometry (HG-AFS) coupled with the multi-syringe flow injection analysis (MSFIA) has been proposed in the application of the Doehlert design to optimise the determination of As and Sb in gouache and tempera children's paints. The determination of the total and bioavailable As and Sb in paint samples from various brands and colours was also investigated. The limits of quantification (LOQ) obtained for the determination of As and Sb were 14.0 and 8.6 ng g-1, respectively. The accuracy and precision of the method were evaluated through recovery tests (by the analyte addition method) at three levels for both elements, and by the analysis of certified reference materials of clay (CRM 052, Loamy Clay 1) and river water (SLRS-4). Twenty paint samples, manufactured in China, Italy, Spain and Brazil, were analysed. The concentrations of As varied between below LOQ ( less then 14 ng g-1) and 136.0 ± 1.1 ng g-1 (average value of 101.0 ng g-1, n = 10), elements) for children when using the analysed paint samples since they do not cause any health risk. The analytical method for the determination of the total and bioavailable As and Sb in children's paints was efficient, accurate and precise.A novel and green hybrid of pipette tip micro solid-phase extraction (PT-μSPE) and supported liquid extraction (SLE) was tailored and established for efficient and sensitive determination of 17β-estradiol (E2) in water samples. The hybrid design used chitin as a solid phase in PT-μSPE and applies the SLE principle on it for micro extraction. The analytical setup was termed as chitin-supported pipette tip-micro liquid extraction (CPT-μLE). E2 is a highly active environmental endocrine disruptor, widely spread in the water environment, and thus it is relevant to develop a novel and noble method for its monitoring at trace concentrations in water.  https://www.selleckchem.com/products/Gefitinib.html  The detection and quantification of E2 were performed via HPLC-UV. Under the optimal conditions, E2 showed excellent linearity in the lower scale range of 0.02-20 ng mL-1, and the correlation coefficient (R2) value was 0.9958. The limit of quantitation (LOQ) and limit of detection (LOD) were 0.01 ng mL-1 and 0.008 ng mL-1, respectively, with inter-day and intra-day precision in the range of 3.2-5.1% and 3.6-4.8%, respectively. The method was successfully applied for the sensitive determination of E2 in real water samples. Overall, the method is simple, rapid, technically innovative, cost-effective, highly sensitive, environment friendly, and highly efficient. Furthermore, this method should allow easy expansion to pharmaceutical and biological samples. Finally, this novel hybrid analytical approach proposes a new direction in sample pre-treatment advancements and should act as a reference for other noble analytical advancements in the trace analysis of various emerging contaminants in environmental and biological matrices.This paper presents a new application for microcomposites based on carbon paste (CP) and La2O3 (LaOX). This simple and versatile microcomposite (LaOX/CPE) was applied toward the determination of paracetamol (PCM) through proton oxidation by square wave adsorptive voltammetry (SWAdV). The anodic peak current for PCM increased by nearly 70.0% compared with an unmodified CP, and the detection limit was 0.020 μmol L-1. The relative standard deviations (RSDs) were 1.0% (n = 7). The accuracy of the new method was evaluated with tap water spiked with known quantities of PCM, while ascorbic acid, caffeine, and acetylsalicylic acid were used for interference studies. Finally, the usefulness of the microcomposite was shown to have acceptable results when applied to detect and quantify PCM in various forms of a pharmaceutical dose, such as solid tablets, fruit-flavored powders for colds and syrups for children.This study presents a practical method for high-precision Cu and Pb isotope determination without column chemistry for bronze materials using MC-ICP-MS. The standard-sample bracketing method combined with Ga internal normalization (SSBIN) was used to correct the instrumental mass bias during Cu isotopic analysis. The effects of acidity mismatch, concentration mismatch, and matrix effect were rigorously evaluated using a Nu Plasma II MC-ICP-MS in the wet plasma mode. The precision and accuracy of this method were verified by measurements of the Chinese bronze standard material GBW02137 over four months. The δ65Cu of GBW02137 was 0.04 ± 0.02‰ (2s standard deviation, n = 44) relative to NIST SRM 976, which is consistent with the recommended value (0.04 ± 0.02‰). GBW02137 could serve as a potential bracketing standard and quality control sample for in situ Cu isotope measurements of ancient bronze artifacts. The 205Tl/203Tl ratio of 2.3889 and an exponential law were used to correct the instrumental mass discrimination during Pb isotopic analysis.