"ZIC2 promotes viability and invasion of human osteosarcoma cells by suppressing SHIP2 expression and activating PI3K/AKT pathways," by Shuaihao Huang and Anmin Jin, J Cell Biochem. 2018; 2248-2257 The above article, published online on 31 August 2017 in Wiley Online Library (https//onlinelibrary.wiley.com/doi/full/10.1002/jcb.26387), has been retracted by agreement between the authors, the journal's Editor-in-Chief, Prof. Dr. Christian Behl and Wiley Periodicals LLC. The retraction has been agreed following an investigation based on allegations raised by a third party. Raw experimental data was not accessible anymore and thus the validity of the overall results could not be confirmed."Downregulation of long noncoding RNA Sox2ot protects PC-12 cells from hydrogen peroxide-induced injury in spinal cord injury via regulating the miR-211-myeloid cell leukemia-1 isoform2 axis," by Dong Yin, Xiaoqing Zheng, Jianxiong Zhuang, Liangze Wang, Bin Liu, Yunbing Chang, J Cell Biochem. 2018; 9675-9684 The above article, published online on 26 August 2018 in Wiley Online Library (https//onlinelibrary.wiley.com/doi/full/10.1002/jcb.27280), has been retracted by agreement between the authors, the journal's Editor-in-Chief, Prof. Dr. Christian Behl and Wiley Periodicals LLC. The retraction has been agreed following an investigation based on allegations raised by a third party. The authors asked to retract this manuscript as some data and experiments are flawed and validity of the overall results could not be confirmed."Downregulation of lncRNA TUG1 contributes to the development of sepsis-associated acute kidney injury via regulating miR-142-3p/sirtuin 1 axis and modulating NF-κB pathway," by Xiaodi Liu, Chengying Hong, Shipin Wu, Shiling Song, Zhi Yang, Lin Cao, Tongwei Song, and Ying Yang, J Cell Biochem. 2019; 11331-11341 The above article, published online on March 4, 2019 in Wiley Online Library (https//onlinelibrary.wiley.com/doi/full/10.1002/jcb.28409), has been retracted by agreement between the authors, the journal's Editor in Chief, Prof. Dr. Christian Behl, and Wiley Periodicals LLC. The retraction has been agreed following an investigation based on allegations raised by a third party. The authors admit that the experimental results are flawed, and the overall conclusions of this manuscript are not reliable."microRNA-383 suppresses the PI3K-AKT-MTOR signaling pathway to inhibit development of cervical cancer via downregulating PARP2," by Peng Teng, Yan Jiao, Min Hao, Xin Tang, J Cell Biochem. 2018; 5243-5252 The above article, published online on 13 December 2017 in Wiley Online Library (https//onlinelibrary.wiley.com/doi/full/10.1002/jcb.26585), has been retracted by agreement between the authors, the journal's Editor-in-Chief, Prof. Dr. Christian Behl and Wiley Periodicals LLC. The retraction has been agreed following an investigation based on allegations raised by a third party. The authors admit errors in the study design that render the results too preliminary and not reliable.
  An international multi-disciplinary initiative, jointly supported by American College of Rheumatology (ACR) and European League Against Rheumatism (EULAR), is underway to develop new rigorous classification criteria to identify patients with high likelihood of Antiphospholipid Syndrome (APS) for research purposes. We applied an evidence- and consensus- based approach to identify candidate criteria and develop a hierarchical organization of criteria within domains.
 
  During Phase I, the APS classification criteria Steering Committee used systematic literature reviews and surveys of international APS physician scientists to generate a comprehensive list of items related to APS. In Phase II, we reviewed the literature, administered surveys, formed domain subcommittees, and used Delphi exercises and nominal group technique to reduce potential APS candidate criteria. Candidate criteria were hierarchically organized into clinical and laboratory domains.
 
  Phase I generated 152 candidate criteria, expanded to 261 will be used for real-world case collection and further refined, organized, and weighted to determine an aggregate score and threshold for APS classification.
  The association between dietary antioxidant quality score (DAQS) and handgrip strength (HS) and handgrip endurance (HE) is still unclear. We aimed to investigate whether adherence to dietary antioxidant quality score (DAQS) is associated with handgrip strength (HS) and handgrip endurance (HE) amongst adults in Tehran.
 
  This cross-sectional study was conducted on 270 (43.7% males, mean age 37years and 56.3% females, mean age 35years) apparently healthy adult subjects (53.2% were married) selected from different parts of Tehran, Iran.  https://www.selleckchem.com/products/YM155.html  Dietary intake was assessed using a 168-item validated food frequency questionnaire. DAQS was calculated using antioxidant-nutrient intake. Body composition was measured using a body composition analyser. Handgrip strength and endurance were measured by a digital handgrip dynamometer. Relative muscle strength was expressed as the ratio of handgrip strength by body mass index (BMI).
 
  The results showed that DAQs had no significant association with HS (P=.67, adjusted R
  =.60) nked to HE. Dietary intake of vitamin C and vitamin E are associated with higher relative muscle strength. It is evident that more prospective studies are needed to confirm the veracity of our results.
  To compare the effect of preventing radiographic progression (in its 3 components) of tocilizumab (TCZ) monotherapy with those of TCZ combined with methotrexate (TCZ+MTX), and to evaluate possible effect modifiers.
 
  Randomized trials comparing TCZ-monotherapy with TCZ+MTX combination therapy regarding radiographic progression were analyzed on individual patient (n=820) data level for early as well as established RA patients using mixed-effects models. Outcomes were not having radiographic progression after 2 years (i.e., preventing radiographic progression), respectively in total Sharp van der Heijde (SvdH) score, in erosion score and in joint space narrowing (JSN) score. Effect modification by baseline joint damage, disease duration and DAS28 was studied.
 
  Overall, TCZ+MTX was more effective in preventing radiographic progression regarding total SvdH scores compared to TCZ-monotherapy. However, in early RA patients with more joint damage (RR 1.02 vs. 0.91 for the less damage group), or a lower DAS28 (RR 1.