The purpose was to compare the effects of protein (whey protein) and carbohydrate supplementation and protein alone both combined with resistance training on muscle strength, muscle mass and total training volume progression in untrained young men.  https://www.selleckchem.com/products/baxdrostat.html  Resistance training was performed using the leg press and knee extension until concentric failure (8-12 repetition maximum), three times a week for eight weeks. Muscle strength and muscle cross-sectional area were assessed before and after training. Total training volume progression was calculated considering the first and eighth week. Seventeen men completed the study (protein and carbohydrate, n=9, age 23.44 ± 4.56 years, weight 62.13±6.17 kg, height 1.75±0.02 m, body mass index 20.29±2.08 kg/m2; protein, n=8, age 24.63±2.39 years, weight 69.01±5.57 kg, height 1.77±0.07 m; body mass index 21.64±1.05 kg/m2. Both protocols showed similar increases in muscle strength (effect size protein and carbohydrate=1.28; protein=0.97; p0.05). Protein and carbohydrate supplementation combined with resistance training does not induce greater gains in muscle strength, hypertrophy and total training volume compared to resistance training combined with protein alone in untrained individuals.Health care workers are subjected to particular job strains. Besides workload, exposure to the risks of violence and traumatic experiences can result in negative health effects. To date, there are hardly any preventive interventions. Supported by the German Innovationsfonds, we want to evaluate the effectiveness of a more intensive intervention for health care workers, the Creative Strengthening Groups. In this randomised controlled trial, 366 participants will be assigned to the intervention or the control group. The intervention group will participate in the Creative Strengthening Groups. At baseline and follow-up, all participants will complete questionnaires. The primary outcome is the change in job satisfaction as measured with the validated Copenhagen Psychosocial Questionnaire (COPSOQ). Secondary outcomes will be obtained by questionnaires that include items on psychosocial working conditions and organisational changes. We hypothesise that participation in the UPGRADE intervention will improve job satisfaction and thus constitute a structural and behavioural prevention strategy for the promotion of psychological well-being of health care workers.
  Gender Dysphoria (GD, formerly known as transsexualism) describes distress and impairment in an individual caused by the incongruence between the experienced gender and the sex assigned at birth (Gender Incongruence GI). Transgender health care focusses on gender-affirmative treatments (e. g., hormone therapy) and associated needs (e. g., psychotherapy). Moreover, genital surgery is considered an effective treatment to reduce GI/GD and improve mental health and quality of life. Interdisciplinary cooperation between the associated medical facilities is regarded as evidence-based health care.
 
  To date, THC is delivered in zwei different health care settings interdisciplinary and centralized from one medical institution vs. decentralized, spread over several medical institutions. In Germany, individuals with GI/GD access health care mostly in decentralized structures. The consequences of feminizing genital surgery carried out in centralized and decentralized health care structures in terms of quality and effectiveness have not been investigated so far. The goal of the TransCare study is to prospectively examine individuals with GI/GD seeking feminizing genital surgery regarding demographics and clinical characteristics as well as to analyze the influence of centralized and decentralized health care settings on the psychosocial and clinical outcome.
 
  To recruit a valid and comprehensive sample, participants were questioned prospectively.
 
  The results of the study should help gain new insights into the influence of centralized and decentralized health care settings carrying out feminizing genital surgery on psychosocial and clinical outcomes for the patients.
 
  Based on the TransCare study, we suggest that health care should be improved according to individual patient needs.
 Based on the TransCare study, we suggest that health care should be improved according to individual patient needs.The concept of mentalization has attracted broad clinical and scientific interest, particularly because of its high clinical and therapeutic relevance. To make this concept accessible for empirical research, the 8-item Reflective Functioning Questionnaire (RFQ-8) was developed, which comprises 2 subscales tapping into uncertainty about mental states (or hypomentalizing), and certainty about mental states (i. e. hypermentalizing). Although first psychometric examinations have evaluated the RFQ-8 positively, these findings must be interpreted with caution for methodological reasons. The aim of this study was the psychometric evaluation of the German version of the RFQ-8 in a large general population sample (n=2477). Various confirmatory and exploratory factor analyses indicated that the originally introduced 2-factor solution is mis-specified. Instead, the RFQ-8 seems to cover a unidimensional construct. Having excluded 2 items due to their insufficient psychometric qualities, the 6-item measure (RFQ-6) showed high internal consistency (McDonald's ω=0,88) as well as significant rank correlations with depression, anxiety and bodily complaints. Considering the psychometric limitations of the RFQ-8, its use in clinical routine and research should be viewed very critically, particularly with respect to its ability to assess hypermentalizing.
  In Germany, waiting times for outpatient psychotherapy are on average 5 months long. Guided web-based interventions can be implemented to reduce depressive symptoms during waiting times. The study aims to explore how patients experience the usage of a web-based intervention for mood enhancement.
 
  Patients on the waiting lists of cooperating outpatient clinics were invited to participate in the study and apply a web-based intervention for mood enhancement. Eleven participating patients were interviewed about their experiences with the intervention. The data was analyzed based on the Grounded-Theory methodology.
 
  Three categories could be derived from the data prior expectations, experiences with the intervention and factors influencing adherence. The web-based intervention was experienced very differently and was associated with both positive and negative experiences. The participants could be grouped into 3 user types.
 
  Not all patients report positive experiences with the intervention and some fail to adhere.