The issues faced by young people transitioning out of government care are complex, and improving outcomes requires the collaboration of multiple stakeholders (Lopez & Allen, 2007).
 
  In Vancouver, Western Canada, 60 agencies and 20 youth from government care are working in partnership using a collective impact approach to address the systemic issues and barriers to healthy development that youth from care experience. Collective impact is an approach to tackling complex social problems which requires collaboration across government, business, funders, charitable organizations, and community members to achieve significant and lasting social change (Hanleybrown et al., 2012). The Vancouver collective operates working groups (co-chaired by youth with care experience) that are addressing challenges in the areas of education, employment, housing, meaningful connections (e.g., sustainable family-type supports), health, wellness and culture.
 
  A mixed-method evaluation has included quantitative and qualitative data, collected through outcomes, diaries, surveys, and focus groups, to measure process and outcomes.
 
  Findings help to inform the ongoing development and activities of the collective. Findings indicate the collective is making progress in meeting its goals. Partners continue to be engaged and committed to improving outcomes for youth transitioning out of care, and there are improvements in a number of key areas such as education, collaborative working, and youth engagement.
 
  A collective impact approach that includes youth's voices, and collaboration across multiple stakeholders, can increase the likelihood of improving outcomes for young people transitioning out of government care.
 A collective impact approach that includes youth's voices, and collaboration across multiple stakeholders, can increase the likelihood of improving outcomes for young people transitioning out of government care.
  Children exposed to violence are at risk of a range of adverse outcomes. Given the unique cultural and social context, understanding what fosters children's resilience in resource-limited areas such as sub-Saharan Africa, is vital.
 
  Using data from the International Survey of Children's Well-Being (ISCWeB), this paper explores individual-, family-, and school-level factors associated with positive outcomes for children who have experienced some form of violence in Khomas region, Namibia.
 
  Using a cross-sectional survey design, the ISCWeB questionnaire, assessing cognitive, affective, and psychological dimensions of well-being, child protection factors and violence exposure was administered to 2124 Grade four and six children.
 
  Our sample had a mean age of 11.2 years.  https://www.selleckchem.com/products/u18666a.html  Overall, 56.8 % of children reported at least one incident of violence from an adult caregiver at home and 86.0 % of children reported some form of peer violence at school. Materially deprived children experienced higher incidence of both family and peer violence. The quality of children's relationships at home (β = 0.17, p < 0.001), and school (β = 0.07, p < 0.001) emerged as important protective factors for children's well-being for both types of violence, suggesting that supportive family and school relationships may be more important to the subjective well-being of children who experienced violence than material wellbeing, violence severity, and individual child factors.
 
  Providing positive social interaction and emotional security in contextually and culturally appropriate ways within children's proximal systems should be prioritized while challenging norms that support violence in Namibian families and schools.
 Providing positive social interaction and emotional security in contextually and culturally appropriate ways within children's proximal systems should be prioritized while challenging norms that support violence in Namibian families and schools.
  the frequency of distal femur fractures in the elderly is rapidly increasing. A study of these fractures was conducted in our center in order to evaluate the comorbidities and the mortality associated with this entity.
 
  all the distal femur fractures by low energy in patients over 65 years old at a tertiary center were included, between January 2010 and December 2016. Baseline characteristics, the type of fracture, comorbidities, and functional status before admission, were collected. The relationship of each of these variables to the final functional class, immediate and late complications and mortality during the follow-up. Fifty-nine patients were included, with a median age of 85.3 years (IQR 78.6-91.6). Fifty-one patients were women. In 10 patients, the fractures were atraumatic (postural change mainly in non-walking patients), and in 54 of the cases were treated surgically (6 with retrograde intramedullary nailing and 48 with lateral locking plate). The median time to surgery was 4.5 days (IQR 2-6) a time to surgery.
  To determine whether vaginal progesterone for programmed endometrial preparation is noninferior to intramuscular progesterone in terms of live birth rates from frozen embryo transfer (FET).
 
  Three-armed, randomized, controlled noninferiority trial.
 
  Multicenter fertility clinic.
 
  A total of 1,346 volunteer subjects planning vitrified-warmed transfer of high-quality nonbiopsied blastocysts were screened, of whom 1,125 subjects were ultimately enrolled and randomly assigned to treatment.
 
  The subjects were randomly assigned to receive, in preparation for FET, 50 mg daily of intramuscular progesterone (control group), 200 mg twice daily of vaginal micronized progesterone plus 50 mg of intramuscular progesterone every third day (combination treatment), or 200 mg twice daily of vaginal micronized progesterone.
 
  The primary outcome was live birth rate per vitrified-warmed embryo transfer. The secondary outcomes were a positive serum human chorionic gonadotropin test 2 weeks after FET, biochemical pregnancy loss, clinical pregnancy, clinical pregnancy loss, total pregnancy loss, serum luteal progesterone concentration 2 weeks after FET, and patient's experience and attitudes regarding the route of progesterone administration, on the basis of a survey administered to the subjects between FET and pregnancy test.
 
  A total of 1,060 FETs were completed. The live birth rate was significantly lower in women receiving only vaginal progesterone (27%) than in women receiving intramuscular progesterone (44%) or combination treatment (46%). Fifty percent of pregnancies in women receiving only vaginal progesterone ended in miscarriage.
 
  The live birth rate after vaginal-only progesterone replacement was significantly reduced, due primarily to an increased rate of miscarriage. Vaginal progesterone supplemented with intramuscular progesterone every third day was noninferior to daily intramuscular progesterone, offering an effective alternative regimen with fewer injections.
 
  NCT02254577.
 NCT02254577.