https://www.selleckchem.com/products/a-1210477.html The biggest flaws in the collective literature are the lack of high-quality prospective studies, a paucity of long-term data and the heterogeneity of utilized outcome measures between studies. Cite this article EFORT Open Rev 2021;6118-129. DOI 10.1302/2058-5241.6.200076.Osteoarthritis of the medial compartment, where the lateral compartment and patella-femoral joint are relatively spared, is a common orthopaedic presentation.Most frequently, the treatment of choice would be a total knee replacement, which involves removing healthy joint surfaces in such patients.Arthroscopic debridement in the osteoarthritic knee has fallen out of favour due to poor clinical results.A trend has developed towards less invasive surgery with uni-compartmental knee replacement (UKR) and high tibial osteotomy (HTO) gaining increasing popularity.Surgeons differ in their relative indications and contraindications to performing these procedures.Total knee replacement (TKR) continues to have the lowest overall revision rate of the available options.Growing evidence demonstrates more favourable patient-reported outcome measures in UKR and HTO patients, compared to TKR.Knee joint distraction (KJD) has been demonstrated as an alternative method of treatment in such patients. Cite this article EFORT Open Rev 2021;6113-117. DOI 10.1302/2058-5241.6.200102.The number of rotating-hinge total knee arthroplasties (RH-TKAs) is increasing. As a result, the number of complications related to these procedures will also increase.RH-TKAs have the theoretical advantage of reducing bone implant stresses and early aseptic loosening. However, these implants also have complication rates that cannot be ignored. If complications occur, the options for revision of these implants are limited.Dislocation of RH-TKAs is rare, with an incidence between 0.7% and 4.4%. If it occurs, this complication must be accurately diagnosed and treated quickly due to the high incid