https://www.selleckchem.com/products/CP-690550.html This paper demonstrates modelling of the aerobic granular sludge (AGS) process with the pseudo-analytical solutions (PAS) of a biofilm model. A MATLAB programmed graphical user interface platform was developed to facilitate the model calculation and access. Model calibration and validation were carried out through using experimental data collected from a granular sludge sequencing batch reactor operation. The experimental and modelling results identified the distribution of heterotrophs and nitrifiers on the AGS and its contribution to the performance of wastewater treatment. The model could describe multi-species biofilms according to the distinguishing features among the three levels of PAS models. The models demonstrated increasing degrees of interaction (no interaction, competition for nitrogen and layering and protection) between heterotrophs and nitrifiers. Modelling the AGS process using PAS increases the accessibility of the simulation of multiple species in both biofilm and suspended biomass.Fe3O4 nanoparticles, used as peroxidase mimetics, exhibit splendid future in the biomedical field. However, the functionalization on Fe3O4 nanoparticles always goes with the loss of superparamagnetism and decrease in peroxidase-activity. Here, we synthesized green polyethylene glycol (PEG)-functionalized magnetic/N-trimethyl chitosan (CS) hybrid nanoparticles (Fe3O4@PAA/TMC/PEG NPs) with improved water dispersibility, superparamagnetism, high saturation magnetization and well peroxidase-like activity. The functionalized coating was divided in two steps, one involved a cross-linked PEG/PAA/CS middle layer to protect the nanocrystal Fe3O4 from oxidization, the other was a hydrophilic PEG/TMC outer layer improving the water dispersion, biocompatibility, as well as supplying positive quaternary ammonium groups for a potential increase of cell binding efficiency. The structure, composition and morphology of Fe3O4@PAA/TMC/PE