https://www.selleckchem.com/products/Gefitinib.html The reliable identification of fentanyl and its analogs is of great significance for public security. However, with the growing prevalence of fentanyl compounds, current analytical strategies cannot fully meet the need for fast and high-throughput detection. In this study, a simple, rapid, and on-site analytical protocol was developed based on a miniature mass spectrometer. A dramatically simplified workflow was implemented using matrix-assisted ionization, bypassing complex sample pretreatment and chromatographic separation. The tandem mass spectrometry (MS/MS) capability afforded by the miniature ion trap mass spectrometer facilitated the investigation of fragmentation patterns for 49 fentanyl analogs during collision-induced dissociation, revealing valuable information on marker fragment ions and characteristic neutral loss. Calculations on Laplacian bond order values further verified the mass spectrometric behavior. A computation-assisted expandable mass spectral library was constructed in-house for fentanyl compounds. Smart suspect screening was carried out based on the full-scan MS and MS/MS data. The present study demonstrates an appealing potential for forensic applications, enabling streamlined screening for the presence of illicit fentanyl compounds at the point of seizures of suspect samples.We report metal-free bond activation by the carboranyl diphosphine 1-PtBu2-2-PiPr2-C2B10H10. This main group element system contains basic binding sites and possesses the ability to cycle through two-electron redox states. The reported reactions with selected main group hydrides and alcohols occur via the formal oxidation of the phosphine groups and concomitant reduction of the boron cage. These transformations, which are driven by the cooperation between the electron-donating exohedral substituents and the electron-accepting cluster, differ from those of "regular" phosphines and are reminiscent of oxidative addition