https://www.selleckchem.com/products/FK-506-(Tacrolimus).html 0001] and PM10 [slope = 0.46 (±0.09); p-value less then 0.0001] samples. Measurements at the Harvard Supersite and at EPA RadNet sites are highly correlated for both α-activities [slope = 0.17 (±0.02), p-value less then 0.0001] and β-activities [slope = 0.30 (±0.05), p-value less then 0.0001]. Additionally, we identified several significant predictors for PM2.5 α-activities. This novel method we developed to measure α- and β-activities from archived filters will make it possible to assess the retrospective particle radioactivity exposure for future epidemiological studies.Prenatal hydroxylated polychlorinated biphenyls (OH-PCBs) exposure may disrupt fetal brain development during the critical period of thyroid hormone (TH) action. However, there are limited studies on the OH-PCB transfer to the fetal brain, particularly in primates. In this study, we selected the Japanese macaque (Macaca fuscata) as a model animal for the fetal transfer of OH-PCBs in humans and revealed OH-PCB concentrations and their relationships in maternal and fetal blood, liver, and brain. l-thyroxine (T4)-like OH-PCBs including 4OH-CB187, a major congener in humans, were found in high proportions in the blood, liver, brain, and placenta of pregnant Japanese macaques. OH-PCBs were detected in the fetal brain and liver in the first trimester, indicating their transfer to the brain in the early pregnancy stage. 4OH-CB187 and 4OH-CB202 were the major congeners found in fetal brain, indicating that these T4-like OH-PCBs are transported from maternal blood to the fetal brain via the placenta. These results indicate that further studies are needed on the effects of OH-PCBs on the developing fetal brain.Interlayered thin-film nanocomposite membranes (TFNi) are an emerging type of membranes with great potential to overcome the permeability-selectivity upper bound of conventional thin-film composite (TFC) nanofiltration and reverse osmosis me