https://www.selleckchem.com/products/U0126.html 05). EEAI has shown strong antioxidant effects in the scavenging of DPPH, superoxide anion, hydrogen peroxide, and nitric oxide. EEAI also has a strong protective effect of UV-induced plasmid pBR322 DNA cleavage and Fenton-induced DNA damage. Overall, the results revealed that Abutilon indicum has a cytoprotective, potent antioxidant and DNA protective effect that provide pharmacological credence to justify its overall biological activity. Furthermore, future studies to identifying bioactive molecules and its molecular mechanisms responsible for promising therapeutic applications in the rescue of disease-induced cellular oxidative damage. The effect of anticoagulation control on overall Health-Related Quality of Life (HRQoL) in patients taking warfarin in Malaysia has not been explored yet. Therefore, this study aimed to evaluate HRQoL among patients on warfarin in Malaysia. HRQoL among patients on warfarin was measured using WHOQOL-BREF (World Health Organization Quality of life Assessment Brief Version). Descriptive and inferential statistical analysis was done using Statistical Package for the Social Sciences (SPSS) version 22. Out of 319 patients, more female patients were observed than the males (n=221, 69.3%, and n=98, 30.7% respectively). Mean scores for the physical (61.14±15.96), psychological (68.58±16.11), social (63.55±27.06) and environmental domains (62.78±17.58) were observed. Statistically, a significant association was found between the comorbidities other than CVDs with health satisfaction ( =0.002), physical ( ), psychological ( ), social ( ) and environmental domains of the WHOQOL-BREF. A weak positive correlation between overall health satisfaction and the social domain ( ) and a moderate positive correlation between the physical and environmental domains ( ) of the WHOQOL-BREF were observed. Patients had overall better perceived HRQoL scores in the psychological domain as compared with the rest of