001). Antiseptic containing 0.2% CHX showed the highest cytotoxicity on cells. The remaining viable cell density after administration of 0.2% CHX at a dose of 12.5% for 30 s is 35.19%. The high cytotoxic effect of 0.2% CHX was followed by 0.12% CHX with 0.15% Benzydamine-HCl, PVP-I and 0.15% Benzydamine-HCl groups. The lowest cytotoxic effect was observed for the Essential-Oil containing antiseptic solution. The results of this study show that these five antiseptic agents have variable effects on in vitro HGF proliferation. The doses and administration times of antiseptics should be controlled carefully during dental applications. The results of this study show that these five antiseptic agents have variable effects on in vitro HGF proliferation. The doses and administration times of antiseptics should be controlled carefully during dental applications. Primary dysmenorrhea (PD) is characterized by symptoms including sweating, headache, nausea, vomiting, diarrhea, tremulousness, usually begins adolescence, those can be associated with autonomic dysfunction affecting pulmonary functions. The aim of the present study is to investigate the impacts of PD on pulmonary function tests. A prospective cross-sectional design was selected. All subjects were invited to admit to the Department of Obstetrics and Gynecology outpatient unit for venous blood test detecting the levels of estrogen and progesterone during the follicular and luteal phase of their menstrual cycle. After drawing blood, women were taken to the pulmonary function tests laboratory to perform the test. https://www.selleckchem.com/products/Decitabine.html The comparisons between Group PD and Group Control were performed by the independent samples t-test or Mann-Whitney U test. Intragroup comparisons were completed by paired samples t-test. Results The comparisons between Group PD and Group Control among estrogen and progesterone in follicular and luteal phase, pulmonary function test results did not show any significance (P > 0.05). The intragroup comparisons of estrogen and progesterone levels, and pulmonary functions test results revealed no significant difference (P > 0.05). The present study showed that PD does not influence the spirometric measurements and also respiratory functions are not impaired by the different phases of menstrual cycle. The present study showed that PD does not influence the spirometric measurements and also respiratory functions are not impaired by the different phases of menstrual cycle. Dental professionals are prone to carpal tunnel syndrome (CTS) and other nerve-related disorders as they perform repetitive wrist work with static physical position for long hours. To evaluate the relationship of thumb radial abduction angle with handgrip strength, hand dexterity, and CTS susceptibility among Saudi senior dental students and interns. The study also intends to compare thumb radial abduction angle based on the gender. A convenient sample of 100 Saudi dental students and interns participated in the study. Their handgrip strength, dexterity, and thumb radial abduction angle were measured by the use of Jamar dynamometer, nine-hole peg test, and goniometer, respectively. Questionnaires were distributed among the participants to assess CTS susceptibility and its association with thumb radial abduction angle. Regression analysis, Pearson's correlation, and independent t-test were performed to analyze the data. A significant correlation between thumb radial abduction angle and handgrip strength was observed. An association of handgrip strength with CTS susceptibility was also found. No significant relationships were drawn considering hand dexterity. Handgrip strength and dexterity were found to be higher in males when compared to females, however, females were observed to be more susceptible to CTS. The study concludes a significant association between thumb radial abduction angle and handgrip strength that is further related with CTS. The results of the study can be used as a foundation for several academicians' research in this domain. The study concludes a significant association between thumb radial abduction angle and handgrip strength that is further related with CTS. The results of the study can be used as a foundation for several academicians' research in this domain.Testicular volume (TV) is considered a good clinical marker of hormonal and spermatogenic function. Accurate reference values for TV measures in infertile and fertile men are lacking. We aimed to assess references values for TV in white-European infertile men and fertile controls. We analyzed clinical and laboratory data from 1940 (95.0%) infertile men and 102 (5.0%) fertile controls. Groups were matched by age using propensity score weighting. TV was assessed using a Prader orchidometer (PO). Circulating hormones and semen parameters were investigated in every male. Descriptive statistics, Spearman's correlation, and logistic regression models tested potential associations between PO-estimated TV values and clinical variables. Receiver operating characteristic (ROC) curves were used to find TV value cutoffs for oligoasthenoteratozoospermia (OAT) and nonobstructive azoospermia (NOA) status in infertile men. The median testicular volume was smaller in infertile than that of fertile men (15.0 ml vs 22.5 ml; P less then 0.001). TV positively correlated with total testosterone, sperm concentration, and progressive sperm motility (all P ≤ 0.001) in infertile men. At multivariable logistic regression analysis, infertile status (P less then 0.001) and the presence of left varicocele (P less then 0.001) were associated with TV less then 15 ml. Testicular volume thresholds of 15 ml and 12 ml had a good predictive ability for detecting OAT and NOA status, respectively. In conclusion, infertile men have smaller testicular volume than fertile controls. TV positively correlated with total testosterone, sperm concentration, and progressive motility in infertile men, which was not the case in the age-matched fertile counterparts.We aim to design a new glanuloplasty procedure combined with spongiosum to reduce the incidence of glans dehiscence and coronal fistula after proximal hypospadias repair. Patients who underwent urethroplasty by dorsal preputial island flap for proximal hypospadias between January 2014 and December 2016 were reviewed in this retrospective cohort study. Those who underwent spongiosum-combined glanuloplasty comprised the new-maneuver group, whereas those who underwent conventional glanuloplasty comprised the control group. The incidence of complications was then compared. In the new-maneuver group, dysplastic corpus spongiosum alongside lateral Buck's fascia (0.3-0.4 cm wide) on both sides of the urethral plate was separated from the proximal normal spongy tissue, joining into the glans wings to increase tissue volume and covering the neourethra in the glans penis. In the control group, the neourethra was covered with superficial fascia under the coronal sulcus. As a result, the new-maneuver and control groups comprised 47 and 28 patients, respectively.