https://www.selleckchem.com/products/pk11007.html that differs from their nonmetastatic counterparts, and thus they exhibit different mechanical characteristics. Discrimination between metastatic and nonmetastatic malignant cell-derived exosomes would be of great importance for studying exosome biological functions and using them as diagnostic biomarkers for various tumor types. Our findings further suggest that metastatic tumor cells release exosomes that express increased levels of elastic fiber-associated proteins to preserve their softness.Neural synapses with diverse synaptic functions of short- and long-term plasticity are highly desired for developing complex neuromorphic systems. A memristor with its two terminals serving as pre- and post-neurons, respectively, can emulate two neuronal-based synaptic functions. In this work, multilayer two-dimensional (2D) layered WSe2 nanosheets are synthesized by a salt-assisted chemical vapor deposition (CVD) method. Two-terminal memristors with a planar structure are fabricated based on the CVD-grown triangular WSe2 nanosheets. The fabricated devices exhibit typical bipolar nonvolatile resistive switching behaviors with a high current ON/OFF ratio of up to 6 × 103 and good retention and endurance properties, suggesting good stability and reliability of the WSe2-based memristors. Furthermore, the developed memristors demonstrate synaptic functions of short- and long-term plasticity (STP and LTP), as well as a transition from STP to LTP by applying consecutive pulse voltages. Moreover, the WSe2-based memristors exhibits biological synaptic functions of long-term potentiation and depression, and paired-pulse facilitation. Thus, our 2D WSe2 nanosheet based memristors not only exhibit stable and reliable nonvolatile resistive switching behaviors, but also show potential applications in mimicking biological synapses.Developing earth-abundant and highly efficient electrocatalysts is critical for further development of a system.