https://www.selleckchem.com/products/cid755673.html Lipid drug conjugates (LDCs) which may also be addressed as lipoidal prodrug, are drug molecules that have been covalently linked with lipids like fatty acids, glycerides or phospholipids. Lipid drug conjugates are fabricated with the aim of increasing drug payload and thus prevent leakage of a highly polar drug from a lipophilic matrix. Conjugating lipids to drug molecules improves lipophilicity and also changes other characteristics of drugs.The conjugates possess numerous advantages including enhanced tumor targeting, improved lymphatic system targeting, improved systemic bioavailability and decreased toxicity. Different conjugation approaches, chemical linkers and spacers can be used to synthesize LDCs based on the chemical nature of lipids and bioactive(s). Linkers and/or conjugation techniques determine how bioactive(s) are released from LDCs and considered as a critical parameter for the optimal performance of the LDCs. The purpose of this review is to discuss widely the use of LDCs as an approach for improving therapeutic drug delivery. In this review different conjugation methods, various lipids used for preparing LDCs and advantages of using LDCs are summarized. Even though LDCs might be administered without a delivery system, most of them are incorporated in appropriate delivery system. The lipid moiety in the conjugates may significantly improve loading of bioactive(s) into hydrophobic compartments. This results in formulations with high drug loading and greater stability. Different delivery carriers such as polymeric nanoparticles, micelles, liposomes, emulsions and lipid nanoparticles which have been explored are discussed in this review. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.The inadequate reuse and recycle of construction and demolition waste (C&DW) has been identified as a major issue, as it implies the depletion of natural aggregates, massi