https://www.selleckchem.com/products/defactinib.html 2 years) after injury. On the FFI, low-risk STTGMA stratification was an independent predictor of worse functional outcomes. Similarly, low-risk stratification was a predictor of worse scores on the SMFA dysfunction and daily activity subcategories (both B>10, p<0.05). Low-risk STTGMA stratification predicted worse long-term function. The STTGMA tool was not able to meaningfully stratify risk for post-discharge complications and secondary procedures following ankle fracture. Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence. Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence. Aim of this systematic review is to investigate the incidence of surgical site infections (SSIs) after routine removal of syndesmotic screws (SSs) placed to stabilize syndesmotic injuries. A systematic literature search was performed in the PubMed, Cochrane, and EMBASE databases for studies published online before February 2020, using the key words and synonyms of "syndesmotic screw" and ("ankle fractures" or "syndesmotic injury") and "implant removal". Studies were eligible for inclusion when they described >10 adult patients undergoing elective/scheduled removal of the SS. The 15 included articles were assessed for quality and risk of bias using the Newcastle-Ottawa Scale. Baseline characteristics of the studies, the study population, the intervention, potential confounders and primary outcome (% of SSIs) were extracted using a customized extraction sheet. The primary outcome was presented as a proportion of included patients and as a weighted mean, using inverse variance, calculated in RStudio studies should focus on valid indications for SSR, the influence of prophylactic antibiotics on SSI after SSR, and complications of retaining the syndesmotic screw to enable a fair benefits/risks comparison of routine vs. on-demand removal of the SS. To