https://www.selleckchem.com/products/gsk963.html 6% (13/197) of children in the placebo group. Sensitization occurred in 46.5% (66/142) of participants in the active and 51.7% (76/147) in the placebo group. CONCLUSION An oral bacterial lysate of heat-killed Gram-negative Escherichia coli and Gram-positive Enterococcus faecalis applied during the first 7 months of life did not influence the development of AD, asthma and AR at school age. © 2020 The Authors. Allergy published by John Wiley & Sons Ltd.BACKGROUND Most patients with contact allergy to Asteraceae plants are patch test positive to sesquiterpene lactone mix (SLM). There are several reports among these patients of a flare-up of hand eczema after ingestion of food and beverages originating from Asteraceae plants. AIM To investigate whether German chamomile tea can elicit systemic allergic dermatitis. MATERIAL / METHODS Individuals with or without contact allergy to SLM were patch tested with an extract of German chamomile tea. Six weeks later, they were provoked with capsules containing either freeze-dried German chamomile tea or placebo capsules containing lactose in a double-blind randomized study. A numerical rating scale (NRS) was used to get the volunteers' opinion of the hand eczema status. The study individuals were examined to detect a possible flare-up of healed patch test reactions to chamomile. RESULTS None of the subjects had a flare-up of healed patch test reactions. According to NRS, SLM-positive individuals experienced a significant worsening of hand eczema, independently of whether they received chamomile or lactose capsules. CONCLUSION No evidence suggestive of systemic allergic contact dermatitis was found. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.Silver-Russell syndrome (SRS) is an imprinting disorder characterized by prenatal and postnatal growth retardation, relative macrocephaly, feeding difficulties and body