https://www.selleckchem.com/products/rgt-018.html Results There were significant differences among the groups in all evaluated stretches (15, 20, 25, and 30 mm). The control elastics presented higher average forces numerically and statistically significant for all tested times, except for the elastic used for 1h. The elastics used for 1, 12, and 24h had similar forces among them, with a significant difference to the elastics used for 48h. Conclusion It is recommended to change the intermaxillary elastics after 24 h of use. © Copyright 2019 by Turkish Orthodontic Society.The International Health Regulations, or IHR (2005), establishes timely communication between the World Health Organization (WHO) and Member States to manage acute public health events and protect health security. Experiences of the WHO IHR contact point for the Western Pacific Region demonstrated the communication mechanism has achieved its functions in the Region. • Investment in IHR communication as part of the Asia Pacific Strategy for Emerging Diseases and Public Health Emergencies (APSED III) during peaceful times between public health emergencies builds capacity, confidence and trust in information sharing during emergencies. • IHR communication is integral to the national, regional and global epidemic intelligence and risk assessments system. • Regular simulation exercises (for example, IHR Exercise Crystal) play an important role in testing and strengthening IHR communication. • IHR communication continues to be vital for Member States and WHO country offices to advise on health security. (c) 2019 The authors; licensee World Health Organization.Objective The World Health Organization's guidelines on viral hepatitis testing and treatment recommend prioritizing high prevalence groups. Hepatitis C virus (HCV) infection disproportionately affects people who inject drugs and men who have sex with men, but data on female sex workers (FSW) are limited. The study aimed to determine active HCV infect