https://www.iampsychiatry.uk/adhd-treatment-for-adults/ Adult ADHD and Comorbid Disorders Many adults with ADHD have comorbid conditions such as major depression (Kessler and co., 2006). Many patients who are depressed do not respond well to medication and could be able to benefit from therapy. Neurotransmitters are brain chemicals that regulate and boost levels of certain brain chemicals. The stimulants methylphenidate and amphetamine are often prescribed. Medicines A variety of medications used to treat ADHD in children can be used in adults. However the dosages differ and the drugs can cause negative side effects that aren't common in children. A doctor will take into consideration the individual's medical history, family history, and other health conditions to determine what medication is most suitable for them. The most commonly used ADHD medication is a stimulant. It works by altering the levels of norepinephrine and dopamine in the brain. Stimulants like methylphenidate (also known as Adderall), and dextroamphetamine boost the supply of neurotransmitters that help improve concentration, decrease impulsivity, and reduce aggression. These stimulants are available in different forms, such as liquids, skin patches and chewable tablets. These long-acting stimulants are favored as they lead to better patient compliance and more consistent, long-lasting improvement of symptoms. It is important to keep in mind that comorbidities like anxiety and depression can alter the effectiveness of ADHD medications. It is therefore recommended that these psychiatric issues be treated first before medications be used as a secondary measure. The medications that can be utilized to treat comorbid disorders of mood are atomoxetine (Bupropion) tricyclic antidepressants, and bupropion (Wilens 2004). Certain patients might suffer from a "rebound effect" where their ADHD symptoms get worse after stopping stimulant medication. In these instances, a short trial of a low dose of stimulant