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Why is this drug recommended? The use of oxycodone is to treat moderate to severe pain. Oxycodone extended-release tablets and capsules are used to treat severe pain in patients who cannot be addressed with other medications and are anticipated to require pain medication 24 hours a day for a long time. Pain that can be managed by medication taken as needed shouldn't be treated with oxycodone extended-release tablets or capsules. Only individuals who have been taking opioid drugs for at least one week and are tolerant to their effects should be treated with oxycodone extended-release tablets, extended-release capsules, and concentrated solution. A class of drugs known as opiate (narcotic) medications includes oxycodone.