https://www.selleckchem.com/products/tak-981.html 0, (n = 5). The obtained recoveries were 95.6-100.2 % for VAL and 92.0-98.1 % for LOS which showed the applicability of green, water-compatible and bio-compatibility of the proposed method for neat and selective extraction of VAL and LOS from complicated urine samples. Functionalised nanohybrid hydrogel using L-Histidine (HIS) conjugated chitosan, phyto-synthesised zinc oxide nanoparticles (ZNPs) and dialdehyde cellulose (DAC) was formulated as a sustained drug delivery carrier for the polyphenol drugs - Naringenin (NRG), Quercetin (QE) and Curcumin (CUR). A maximum loading efficiency of 90.55 %, 92.84 % and 89.89 %, respectively were optimised for NRG, QE and CUR in the hybrid hydrogel. The maximum drug release was favoured for the optimum drug loading and at pH-5. HIS-chitosan conjugation stabilised the hydrogel and enabled a sustained drug delivery. Drug release kinetics predicted a non-Fickian diffusion-based mechanism along with polymer erosion. Prominent antimicrobial activity against Staphylococcus aureus and Trichophyton rubrum strains were predicted to evolve based on the synergic formulation. Significant biocompatibility towards L929 cells revealed their support for normal cell survival. Anticancer studies towards A431 cells exhibited excellent cytotoxicity with a 15 to 30-fold increase using the hybrid carrier, compared to the free polyphenol drugs. In order to explore a novel type of agricultural water-retaining agent, borax crosslinked fenugreek galactomannan-borax hydrogel (FGB) was synthesized. The hydrogel was characterized by thermogravimetric analysis, FT-IR, XRD, and SEM. The largest swelling index of FGB (115) was higher than that of guar gum hydrogel (70) at pH 9. The water absorption capacity of sandy soil was studied by mixing the hydrogel with soil, then FGB was evaluated as a latent water retention agent. Results showed that the swelling index of sandy soil increased from 16.28% to 35.53% wit