https://www.selleckchem.com/products/etomoxir-na-salt.html Obesity is a risk factor for many adverse health outcomes. However for some cardiac conditions and cancers, evidence of an "obesity paradox" seems to exist where an elevated body mass index (BMI) is linked to protective effects in mortality and functional outcomes. Within the stroke rehabilitation literature, there are conflicting findings on this phenomenon possibly due to unaccounted for variables, such as comorbid medical conditions. To investigate the association between BMI and functional gains made in acute inpatient stroke rehabilitation, and the effects of multiple confounding variables. Retrospective cohort study. Tertiary academic hospital. Three hundred ninety-two adults following a recent ischemic (82%) or hemorrhagic (18%) stroke with a mean age 62.9 years. Acute inpatient rehabilitation. Functional Independence Measure (FIM) score and BMI. A significant association was found between motor FIM score gains and elevated BMI when BMI was treated as a continuous variable (p < .05).ox" once patient factors and comorbid conditions are taken into account. Diabetes was the single comorbidity tracked that showed a significant association with change in motor function (p = .01). Further studies might explore how the unique interventions of rehabilitation physicians and ancillary health professionals might mitigate the functional debility associated with diabetes and obesity in stroke patients. Metabolomic and preclinical studies suggest that branched-chain amino acids (BCAA) may be inversely associated with neurodegenerative diseases including glaucoma. We therefore assessed the long-term association between dietary intake of BCAA and incident primary open-angle glaucoma (POAG) and POAG subtypes. We followed biennially participants of the Nurses' Health Study (NHS; 65531 women 1984-2016), Health Professionals Follow-up Study (42254 men 1986-2016) and NHSII (66904 women; 1991-2017). Eligible participants w